Chronic Obstruction Pulmonary Disease Analysis

Introduction: Chronic obstruction pulmonary disease (COPD) is characterized by chronic inflammation and irreversible airflow obstruction which causes some structural changes in the lung1. It is the fourth major and leading cause of morbidity and mortality worldwide and it will become third in all major causes of death by 20202. Since two decades, smoking is the major cause of COPD worldwide. This disease is rare in non-smoking person except those who will have exposure of occupational dust, environmental air pollutants or biomass fuel3,4,5. One fourth to one third of all cases of COPD occurs in never smoker population. It means irreversible air flow obstruction may occur in this population6. Studies showed that 23.3% of subjects with
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