Child Psychiatric Disorders: A Case Study
A Head-to-Head Comparison of Aripiprazole and Risperidone for Safety and Treating Autistic Disorders, a Randomized Double Blind Clinical Trial citation rationale subjects measures results Outcomes/ conclusions
Ghanizadeh, A., Sahraeizadeh, A., & Berk, M. (2014). A head-to-head comparison of aripiprazole and risperidone for safety and treating autistic disorders, a randomized double blind clinical trial. Child Psychiatry and Human Development, 45(2), 185-92. doi:http://dx.doi.org.ccbcmd.idm.oclc.org/10.1007/s10578-013-0390-x • “Autism spectrum disorders are a group of neuropsychiatric disorders characterized by the key symptoms of impairments in social relationships, verbal and non-verbal communications, repetitive behaviors, and restricted …show more content…
• Checklist
-examine extrapyramidal symptoms and other adverse effects (weight, height, and blood pressure) • Three patients in each group withdrew from the trial(medical and personal reasons)
• The mean weight and height at baseline between the two groups were not statistically different
• The mean baseline ABC irritability subscales were not significantly different between the groups, but the “decrease in the irritability and agitation subscale score in the aripip-razole group was greater than in the risperidone group.”
• Both medications decreased the ABC irritability subscale
• CGI scores were not significantly different • aripiprazole slightly decreases irritability and agitation earlier than risperidone
• aripiprazole and risperidone are good and equal medications used to treat irritability in autism patients
• it is up to the doctor and patient to decide which medication to use
• a larger group is recommended for further
Ghanizadeh, A., Sahraeizadeh, A., & Berk, M. (2014). A head-to-head comparison of aripiprazole and risperidone for safety and treating autistic disorders, a randomized double blind clinical trial. Child Psychiatry and Human Development, 45(2), 185-92. doi:http://dx.doi.org.ccbcmd.idm.oclc.org/10.1007/s10578-013-0390-x • “Autism spectrum disorders are a group of neuropsychiatric disorders characterized by the key symptoms of impairments in social relationships, verbal and non-verbal communications, repetitive behaviors, and restricted …show more content…
• Checklist
-examine extrapyramidal symptoms and other adverse effects (weight, height, and blood pressure) • Three patients in each group withdrew from the trial(medical and personal reasons)
• The mean weight and height at baseline between the two groups were not statistically different
• The mean baseline ABC irritability subscales were not significantly different between the groups, but the “decrease in the irritability and agitation subscale score in the aripip-razole group was greater than in the risperidone group.”
• Both medications decreased the ABC irritability subscale
• CGI scores were not significantly different • aripiprazole slightly decreases irritability and agitation earlier than risperidone
• aripiprazole and risperidone are good and equal medications used to treat irritability in autism patients
• it is up to the doctor and patient to decide which medication to use
• a larger group is recommended for further