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Cerebral Organoids Research Paper

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Cerebral Organoids Research Paper
The Cerebral Organoid Scrutiny
Since the beginning of history, cerebral disorders affect upward of 213,745 people annually in the 21st century (Muzio). People are constantly on the search for the newest and biggest technological advance, especially if it offers straightforward solutions to major problems that affect people across the globe each and every day; such as Alzheimer's, stroke, trauma and tumors. Your brain is your link between life and death, we must constantly maintain ourselves to avoid these conditions but sometimes it's inevitable. Cerebral organoids are the solution to this past and current matter of dispute, however this is still an exploratory method that many object.
The MIT technology review defines cerebral organoids
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The creation of such medical technology however was not done without steady, deliberate experiments over the past decade.
Kelly Chi, a freelance science and technology journalist from the University of North Carolina, outlined in her article titled the “Scientist” in 2015 the history of cerebral organoids. In 2009, Michael Shen, the professor of medicine at Columbia University Medical Center, and his team discovered a stem cell from which prostate cancer originates known as CARNS, for castration-resistant Nkx3.1-expressing cells (Chi). Because these cells are luminal epithelial, they were forced to use unconventional means of culturing these cells but through a trial and error approach they reached a breakthrough and successfully turned CARNS into organoids. The resulting organoids perfectly matched the characteristics of normal prostate epithelium. The new organoid was then engrafted back into mice and triumphantly generated prostatic tissues. These prostatic organoids will become the infrastructure for the soon to be discovered cerebral organoids. Through the “Nature Protocol Exchange,” a database for scientists to make their research available to the public, Shen’s groundwork falls into the hands of Ankur Singh, the assistant

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