Caffeinated Coffee Case Study

Studies of coffee have been conducted extensively on whether caffeinated coffee is beneficial or harmful but until now health experts cannot prove the future of it. Experts were concerned about caffeine in coffee and they chose coffee to conduct studies on caffeine as it is a widely consumed and accepted food stimulants. There is much debate on the safety of caffeine. The results from studies, even in carefully controlled scientific experiments, were contradictory on the effects of caffeine. Most of the studies were done on laboratory animals so scientists displayed uncertainty on whether those results from the studies could be applied to humans (cite).
The health impact of caffeinated coffee has been controversial. Caffeine is an alkaloid
PD is a degenerative disorder characterized by shaking, stiffness, slow movements and difficulty of balance while AD is a gradual process of neurodegeneration whereby the nerve connections in the brain erode slowly. One of the hallmarks for AD is the Tau protein whereby it kick starts a cascade that eventually leads to the disease. Caffeinated coffee has a positive impact on these symptoms and mechanism involved in these diseases. Caffeine is known to improve motor symptoms. In an American study, half of the group of patients with PD received caffeine treatment while the other half received an inactive placebo component. As a result, there were improvements in the speed of movement and stiffness in the treatment group. Caffeine is theorized to block receptors of A2A adenosine (a substance that plays a role in some of the symptoms of PD) even though studies are still ongoing. (Gordon, Aug 2012). In addition, a Genome Wide Association and Interaction Study (GWAIS) was conducted in the Swedish population and it focused on PD’s communication between gene and environment, particularly on caffeinated coffee consumption and GRIN2A gene that encodes for a subunit of NMDA-glutamate-receptor. It was thus revealed that the carriers of GRIN2A_rs4998386-T allele bears a lower risk of contracting PD. Overall the data in the Swedish population study stated
Caffeine increases the production of adrenocorticotropic hormone in the pituitary gland and as a result, increases cortisol hormone too. A high amount of cortisol hormone causes a few health issues such as overactive immune system, irregular sleep patterns, impaired digestion and depression. However, studies are still ongoing on the pathology of caffeinated coffee and cortisol hormone and no statistics has been proven yet if there was any confirmed study. Though it is theorized that caffeinated coffee induces these detrimental effects, with studies, if conducted in the future, can further show that caffeinated coffee is not perfect anymore. With moderate consumption as mentioned above, these harmful effects can be avoided (Ballantyne, July