Burn Injury Papers
Burn injury is among the most weakening traumas to humans. The rate of burns in the United States of America is estimated to be over 2 million cases per year, with 3,400 deaths per year and about 250000 people are burnt each year in the United Kingdom. Of these, almost 112000 attend an accident and emergency department and about 210 die of their injuries. According to the World Health Organization, it is estimated that about 300,000 dies worldwide each year due to burns. Burn injury causes significant dysfunction of numerous organs in the body (1-4). Extensive burns, Particularly, result in systemic problems for example sepsis (5). Taking care of burned patients imposes a large burden for health care organization. It is further than $500
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For example, mutant mice models allowed us to have an understanding into the genetic pathways involved in diabetes and obesity. Additionally, the rat animal model has helped researchers to find the genetics basis of cardiovascular diseases such as hypertension and atherosclerosis (4, 7). For burn studies, in vitro models have restriction for example low capacity to achieve all forms of burn pathophysiology and/or limitation of the multiple clinical aspects of human burn injury. For these problems, animal models are required to discover the post-burn pathological mechanisms and test novel therapeutic strategies. One of the main limitations in researches of burn treatment is inaccessibility to a proper cases that presents all aspects of burn trauma. Therefore animal models are still necessary for discovering the molecular and cellular characteristics of human burn trauma. Furthermore, for complex structure of burns, a number of different animal models have been developed to study of burn pathophysiology (8-10).
The aim of this study is design an easy, cost-efficient and reproducible technique for establishing coherent burn injuries in a rat burn model, for the evaluation of burn wound in experimental studies. Therefore we define a Standardized scalding burn model in rat. In this regard, template firmly
For example, mutant mice models allowed us to have an understanding into the genetic pathways involved in diabetes and obesity. Additionally, the rat animal model has helped researchers to find the genetics basis of cardiovascular diseases such as hypertension and atherosclerosis (4, 7). For burn studies, in vitro models have restriction for example low capacity to achieve all forms of burn pathophysiology and/or limitation of the multiple clinical aspects of human burn injury. For these problems, animal models are required to discover the post-burn pathological mechanisms and test novel therapeutic strategies. One of the main limitations in researches of burn treatment is inaccessibility to a proper cases that presents all aspects of burn trauma. Therefore animal models are still necessary for discovering the molecular and cellular characteristics of human burn trauma. Furthermore, for complex structure of burns, a number of different animal models have been developed to study of burn pathophysiology (8-10).
The aim of this study is design an easy, cost-efficient and reproducible technique for establishing coherent burn injuries in a rat burn model, for the evaluation of burn wound in experimental studies. Therefore we define a Standardized scalding burn model in rat. In this regard, template firmly