Bone Regeneration Research Paper

A comparison and review of bone regeneration methods after periodontitis
Periodontitis is a very serious oral illness which can ultimately lead to the loss of teeth. The gums get inflamed due to all kinds of bacteria in the plaque surrounding the teeth. The first stages of this disease are reversible and are actually stages of gingivitis. The inflammation that occurs can be reversed by extra attention to (the) oral health, brushing teeth and interdental hygiene. However, when this does not get any attention at an early stage of the disease, gingivitis may turn into the much worse disease periodontitis. The gums are invaded by bacteria and the alveolar bone also gets attacked. This process is enhanced by a relatively severe immune reaction, one that is actually too heavy considering what is happening. This will eventually lead to significant bone
Cell-based therapy is a favored method in regeneration because it allows participation of the cells in the process, genetic modification and they can differentiate into different periodontal tissues. Three components are needed for bone regeneration: cells that can create matrix, growth factors and other stimuli and a scaffold which allows proliferation and supports the tissue.
Regrettably, most of the research that has been done on bone regeneration or bone substitutes covers bone needed for maxillofacial surgeries or when placing implants. Furthermore, most research does not cover whether the method could indeed be used in a clinical setting. There is little research on what would be an effective way to use bone regeneration after periodontitis. Thus this review will attempt to find out whether current methods of bone regeneration are also feasible after periodontitis, and whether new techniques are applicable in the parodontology