Biochemistry

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Topics: Cancer, Oncology
Piperazine (generic, Vermizine) Oral: piperazine citrate tablets equivalent to 250 mg of the hexahydrate; piperazine citrate syrup equivalent to 500 mg of the hexahydrate per 5 mL Praziquantel (Biltricide; others outside the USA) Oral: 600 mg tablets (other strengths outside the USA) Pyrantel pamoate (Antiminth, Combantrin, Pin-rid, Pin-X) Oral: 50 mg (base)/mL suspension; 62.5 mg (base) capsules (available without prescription in the USA) Suramin (Bayer 205, others) Parenteral: ampules containing 0.5 or 1 g powder to be reconstituted as a 10% solution and used immediately Note: Suramin is not marketed in the USA but can be obtained from the Parasitic Disease Drug Service, Centers for Disease Control, Atlanta, 404-639-3670. Thiabendazole (Mintezol) Oral: 500 mg chewable tablets; suspension, 500 mg/mL

Chapter 55. Cancer Chemotherapy
Katzung PHARMACOLOGY, 9e > Section VIII. Chemotherapeutic Drugs > Chapter 55. Cancer Chemotherapy > Cancer Chemotherapy: Introduction Acronyms ABVD: Doxorubicin (adriamycin), bleomycin, vinblastine, dacarbazine CHOP: Cyclophosphamide, doxorubicin (hydroxydaunorubicin), vincristine (oncovin), prednisone CMF: Cyclophosphamide, methotrexate, fluorouracil COP: Cyclophosphamide, vincristine (oncovin), prednisone FAC: Fluorouracil, doxorubicin (adriamycin), cyclophosphamide FEC: Fluorouracil, epirubicin, cyclophosphamide IFL: Irinotecan, fluorouracil, leucovorin MP: Melphalan, prednisone MOPP: Mechlorethamine, vincristine (oncovin), procarbazine, prednisone PCV: Procarbazine, lomustine, vincristine PEB: Cisplatin (platinum), etoposide, bleomycin VAD: Vincristine, doxorubicin (adriamycin), dexamethasone General

Cancer is basically a disease of cells characterized by a shift in the control mechanisms that govern cell proliferation and differentiation. Cells that have undergone neoplastic transformation usually express cell surface antigens that may be of normal fetal type, may display other signs of apparent immaturity, and may exhibit

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