Bio/1101 Unit 1 Study Guide

Satisfactory Essays
Name: Nympha Afriyie
Course: Bio 1101 lab
Due date: February 12 2015
Journal 2
Year: March 5th 2004
Journal Name: 2 (two)
Article title: Genome-Wide Scan Identifies Novel QTL’s For Cholesterol and LDL Levels in F2 [Dahl RxS] Intercross Rats
Authors: Victoria L.M, Tamara Didishvili, Lyle V. Lopez, Richard H. Myers, Nelson Ruiz-Opazo

1. What is the disease name of the model/study organism?
Answer: the disease name of the model/study organism is, Coronary artery disease
2. What is one piece of interesting information found in the introduction?
Answer: one piece of interesting information I found in the introduction was that, low-density lipoprotein cholesterol (LDL) has been shown to be the most predictive of atherogenic susceptibility6 and has been demonstrated to exhibit oxidative susceptibility, which then relates to pathogenic oxidative processes implicated in coronary atherosclerotic plaque progression and destabilization.(page 446)
…show more content…
What is the major question and/or hypothesis in the journal article?
Answer: the major question and or hypothesis studied in this article is that the more cholesterol present the more coronary heart disease and stroke would be available among people.
4.
a) Where did they sample?
Answer: they did sample in Western countries. (Page 446 2nd sentence)
b) How did they sample?
Answer: For the samples they performed a 121-marker, total genome-analysis of an F2[Dahl RS]-intercross selected for contrasting parental strain susceptibilities for hyperlipidemia on regular rat diets at 6 months of age.(446)
c) Number of samples taken?
Answer: the number of samples taken was four (4)

5.
I. Describe the

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