Antibiotic Resistant Bacteria
Read pg 112 -113 & 275 – 277 of you text book.
Use this information plus information from secondary sources to answer the following questions so you will have a case study on antibiotic resistant bacteria. In this case study you will need to show how an environmental change can lead to a change in a species.
Note: this will also cover content in the Search for Better Health topic. 1. Outline the purpose of anti-biotics
Antibiotics are used for treatment or prevention of a bacterial infection.
2. Define the term resistance
The refusal to accept or comply with something; the attempt to prevent something by action or argument.
3. Describe what is meant by the term ‘antibiotic resistance’
When bacteria and other microorganisms are able to resist the effects of an antibiotic to which they were once sensitive. Antibiotic resistance comes from the overuse of antibiotics.
4. Identify a species of bacteria that has become resistant to antibiotics Staphylococcus aureus 5. Describe the change that occurred within the species.
Aminoglycoside antibiotics were once effective against staphylococcal infections, and now are not.
6. Describe the change in the environment that occurred.
“Strains evolved mechanisms to inhibit the aminoglycosides' action, which occurs via protonated amine and/or hydroxyl interactions with the ribosomal RNA of the bacterial 30S ribosomal subunit”
7. Identify whether the environmental change was a physical or chemical change. Chemical 8. identify and describe the selective pressure acting on the organism as a result of the environmental change.
The selective pressure on the Staphylococcus aureus bacteria is the antibiotic. Strains of the bacteria that are resistant to the antibacterial drug multiply through the process of natural selection and then the bacterium becomes resistant to the antibiotic.
9. Explain how 6 lead to 5.
?
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