Aripiprazon Case Summary

SEIZURES WITH LOW DOSE OF ARIPIPRAZOLE IN MENTAL RETARDATION- A FIRST CASE REPORT.
ABSTRACT
Aripiprazole is considered as a third generation antipsychotic and known for its unique partial agonist activity at dopamine D2 and serotonin 5-HT1Areceptors. Partial antagonist action at serotonin 5-HT2Areceptors . The common neurological side effects are extra pyramidal symptoms, headache, insomnia and drowsiness. Seizures had been reported in 2 cases of adults with normal intelligence and 1 in healthy 3 year old child after accidental consumption of 30 mg of aripiprazole(4) . Here we report a 21 year old female with intellectual disability developed seizure with low lose of aripiprazole. To our knowledge, this is the first reported case of aripiprazole induced seizures in mental retardation.

BACKGROUND
Seizures had been reported in 2 cases of adults with normal intelligence and 1 in healthy 3 year old child after accidental consumption of 30 mg of aripiprazole(4) . Here we report a 21 year old female with intellectual disability developed seizure with low lose of aripiprazole. To our knowledge, this is the first reported case of aripiprazole induced seizures in mental