Antithrobotic Drug Heparin
Heparin
Heparin
Heparin, otherwise known as Hep-Lock, Hep-Lock U/P, or Monoject Prefill, is an anticoagulant and an antithrombotic drug. According to Linda Skidmore-Roth’s book entitled Mosby’s Drug Guide for Nursing Students (2013), heparin is used to prevent deep vein thrombosis (DVT) and pulmonary emboli (PE), myocardial infarction, open heart surgery, disseminated intravascular clotting syndrome, and atrial fibrillation with embolization. It is also used as an anticoagulant in transfusion and dialysis procedures, to maintain patency of indwelling venipuncture devices, and diagnosis and treatment of disseminated intravascular coagulation (DIC) (p.517). In Pharmacology and the Nursing Process (2013), Pharmaceutics …show more content…
Because heparin is an anticoagulant, it is also called antithrombotic because it works to prevent the formation of a clot or thrombus. All anticoagulants work in the clotting cascade but so at different points. This specific drug prevents conversion of fibrinogen to fibrin and prothrombin by enhancing inhibitory effects of antithrombin III. Heparin works by binding to antithrombin III, turning off three main activating factors. The overall effect of heparin is that it turns off the coagulation pathway and prevents clots from forming (Lilley, Rainforth Collins, Snyder, 2013, …show more content…
For instance: Dextran, dipyridole, ticlopidine, clopidogrel, and presgrel increase the action of heparin, while Digoxin and Nicotine decrease the action. Lab results show an increased ALT, AST, INR, pro-time, PTT, and potassium. It also shows a decrease in platelets, triglycerides, cholesterol, and plasma free fatty acids. Though some patients may not experience an interaction with another drug, some may encounter some unpleasant side effects. Some of the adverse effects of this medication can be life-threatening such as Hematuria of the genitourinary system, as well as hemorrhage, thrombocytopenia, anemia, and anaphylaxis in other parts of the body. Some of the more common events include fever, rash, chills, and headaches
Heparin
Heparin, otherwise known as Hep-Lock, Hep-Lock U/P, or Monoject Prefill, is an anticoagulant and an antithrombotic drug. According to Linda Skidmore-Roth’s book entitled Mosby’s Drug Guide for Nursing Students (2013), heparin is used to prevent deep vein thrombosis (DVT) and pulmonary emboli (PE), myocardial infarction, open heart surgery, disseminated intravascular clotting syndrome, and atrial fibrillation with embolization. It is also used as an anticoagulant in transfusion and dialysis procedures, to maintain patency of indwelling venipuncture devices, and diagnosis and treatment of disseminated intravascular coagulation (DIC) (p.517). In Pharmacology and the Nursing Process (2013), Pharmaceutics …show more content…
Because heparin is an anticoagulant, it is also called antithrombotic because it works to prevent the formation of a clot or thrombus. All anticoagulants work in the clotting cascade but so at different points. This specific drug prevents conversion of fibrinogen to fibrin and prothrombin by enhancing inhibitory effects of antithrombin III. Heparin works by binding to antithrombin III, turning off three main activating factors. The overall effect of heparin is that it turns off the coagulation pathway and prevents clots from forming (Lilley, Rainforth Collins, Snyder, 2013, …show more content…
For instance: Dextran, dipyridole, ticlopidine, clopidogrel, and presgrel increase the action of heparin, while Digoxin and Nicotine decrease the action. Lab results show an increased ALT, AST, INR, pro-time, PTT, and potassium. It also shows a decrease in platelets, triglycerides, cholesterol, and plasma free fatty acids. Though some patients may not experience an interaction with another drug, some may encounter some unpleasant side effects. Some of the adverse effects of this medication can be life-threatening such as Hematuria of the genitourinary system, as well as hemorrhage, thrombocytopenia, anemia, and anaphylaxis in other parts of the body. Some of the more common events include fever, rash, chills, and headaches