Anti-Inflammatory Drug
Aspirin
Background
Aspirin
Aspirin, or acetylsalicylic acid (ASA) is a salicylate drug, and is generally used as an analgesic (something that relieves pain without producing anaesthesia or loss of consciousness) for minor aches and pains, to reduce fever (an antipyretic), and also as an anti-inflammatory drug.
Aspirin works by prohibiting biological substances such as prostaglandins. Many different prostaglandins exist in the human body each serving a plethora of physical functions. Prostaglandins are amongst the chemicals produced by the body’s immune system when it fights off pathogens. These pathogens usually cause inflammation and pain. Following infection, prostaglandins are also produced the hypothalamus, the brain’s centre for controlling body temperature, resulting in a rise in temperature. Inhibiting their production consequently inhibits pain and temperature rise
Another type of prostaglandins is found in the blood causes platelets to stick together causing thrombosis. Again aspirin inhibits these prostaglandins.
The many kinds of prostaglandin are synthesized by a combination of biochemical pathways. However, all pathways share a common stage facilitated by an enzyme called COX. Aspirin is an enzyme inhibitor. As you can see from figure 2 It suppresses the action of the enzyme COX, stopping the production of prostaglandin, thus disrupting the pathways to pain, inflammation, elevated temperature and the formation of blood clots.
Enzymes are biological protein catalysts that speed up chemical reactions without being themselves used up themselves in the reaction. Enzymes are protein catalysts that speed up chemical reactions without being themselves used up in the reactions. An enzyme is a huge molecule with an active site that works like a lock that accepts certain substrate (key) . Enzymes are long, linear chains of amino acids that fold to produce many levels of structure (Primary, tertiary and quaternary) . Each amino acid sequence
Background
Aspirin
Aspirin, or acetylsalicylic acid (ASA) is a salicylate drug, and is generally used as an analgesic (something that relieves pain without producing anaesthesia or loss of consciousness) for minor aches and pains, to reduce fever (an antipyretic), and also as an anti-inflammatory drug.
Aspirin works by prohibiting biological substances such as prostaglandins. Many different prostaglandins exist in the human body each serving a plethora of physical functions. Prostaglandins are amongst the chemicals produced by the body’s immune system when it fights off pathogens. These pathogens usually cause inflammation and pain. Following infection, prostaglandins are also produced the hypothalamus, the brain’s centre for controlling body temperature, resulting in a rise in temperature. Inhibiting their production consequently inhibits pain and temperature rise
Another type of prostaglandins is found in the blood causes platelets to stick together causing thrombosis. Again aspirin inhibits these prostaglandins.
The many kinds of prostaglandin are synthesized by a combination of biochemical pathways. However, all pathways share a common stage facilitated by an enzyme called COX. Aspirin is an enzyme inhibitor. As you can see from figure 2 It suppresses the action of the enzyme COX, stopping the production of prostaglandin, thus disrupting the pathways to pain, inflammation, elevated temperature and the formation of blood clots.
Enzymes are biological protein catalysts that speed up chemical reactions without being themselves used up themselves in the reaction. Enzymes are protein catalysts that speed up chemical reactions without being themselves used up in the reactions. An enzyme is a huge molecule with an active site that works like a lock that accepts certain substrate (key) . Enzymes are long, linear chains of amino acids that fold to produce many levels of structure (Primary, tertiary and quaternary) . Each amino acid sequence