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Altered Physiology and Emergency Nursing Care of Patient with Exacerbations of Copd

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Altered Physiology and Emergency Nursing Care of Patient with Exacerbations of Copd
Altered physiology and emergency nursing care of patient with exacerbations of COPD within the first two hours in A&E

Introduction

The following essay will discuss the case of Mr Jones, who was admitted to the A&E department following a worsening of his symptoms of COPD. The focus of the essay is to provide a detailed plan of the management and emergency care of patients with exacerbations of COPD in A&E within the first two hours of their admission.
The essay will guide us through Mr Jones’ stay at the A&E department with regards to the altered physiology of COPD and its acute episodes of exacerbations. Mr Jones’ worsened health condition and physical symptoms will be assessed in the light of his medical history. The author will also analyse the relevant literature and relate the clinical management not only to pathophysiology but also to the evidence base and clinical practice.
The importance of providing patient-centered care will be emphasised in areas of consent and privacy and dignity of the patient. Responsibility and accountability in nursing profession will be underlined in the light of the NMC (2007) Code of Conduct for nurses and midwives. A summary of the main points of the discussed topic will be provided in the conclusion. All literature will be referenced with adherence to the Harvard Referencing System.

Pathophysiology of COPD in acute exacerbations

Exacerbations of COPD can be described as increased airway inflammation and oedema, leading to systemic inflammation causing even more airflow limitation and worsening of ventilation and perfusion (Aaron et al, 2001). It can also be characterised by increased oxygen consumption, altered hypoxic vasoconstriction, and systemic and pulmonary haemodynamic abnormalities (increased cardiac output and increased pulmonary artery pressure) (Bhowmik et al, 2000; Dentener et al, 2001).
The three main factors that contribute to the narrowing of the airways are peribronchial fibrosis,



References: Anthonisen, N.R., Manfreda, J. and Warren, C.P.W. (1987) Antibiotic-therapy in exacerbations of chronic obstructive pulmonary-disease. Annals of International Medicine, 106(2), p. 196-204. Barbera, J.A., Roca, J. and Ferrer, A. (1997) Mechanisms of worsening gas exchange during acute exacerbations of chronic obstructive pulmonary disease. European Respiratory Journal, (10), p. 1285-1291. Barnes, P. J. and Celli, B. R. (2009) Systemic manifestations and comorbidities of COPD. European Respiratory Journal, 33(5). Bhowmik, A., Seemungal, T. A., and Sapsford, R. J. (2000) Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax, p. 55114–55120. Chung, K.F. (2005) The role of airway smooth muscle in the pathogenesis of airway remodelling in COPD. Proceedings of the American Thoracic Society (2), p. 347-354. Corbridge, S., Wilken, L., Kapella, M. C. and Gronkiewicz, C. (2012) An Evidence-Based Approach to COPD. American Journal of Nursing, 112 (3). Danahay, H. and Jackson, A.D. (2005) Epithelial mucus-hypersecretion and respiratory disease. Current Drug Targets – Inflammation and Allergy, 4, p. 651-664. DeGaute, J.P., Domenighetti ,G. and Naeije, R, (1981) Oxygen delivery in acute exacerbation of chronic obstructive pulmonary disease. Effects of controlled oxygen therapy. American Review of Respiratory Disease, 124(1), p. 26-30. Kleinschmidt, P. (2011) Chronic obstructive pulmonary disease and emphysema in emergency medicine, Medscape.com, New York. Medical Research Council Working Party (1981) Long term domi-ciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Report of the Medical Research Council Working Party. Lancet, 8222, p. 681-6. Nussbaumer-Ochsner, Y. and Rabe, K. F. (2011) Systemic manifestations of COPD. Chest, 139(1), p. 165-73. Plant, P.K., Owen, J.L. and Elliott, M.W. (2000) One year period prevalence study of respiratory acidosis in acute exacerbations of COPD: implications for the provision of non-invasive ventilation and oxygen administration. Thorax, 55(7), p. 550-554. Pride, N. and Milic-Emili, J. (2003) Lung mechanics. In: Calverley, P., MacNee, W., Pride, N., and Rennard, S. editors. Chronic obstructive pulmonary disease, 2nd ed. London: Arnold. Ram, F.S.F, Lightowler, J.V.J. and Wedzicha, J.A. (2003) Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease. The Cochrane Library, 3(3). Rochester, D.F. and Braun, N.M. (1985) Determinants of maximal inspiratory pressure in chronic obstructive pulmonary disease. The American Review of Respiratory Disease (132), p. 42–47. Singh, J.M., Palda, V.A., and Stanbrook, M.B. (2002) Corticosteroid therapy for patients with acute exacerbations of COPD: a systematic review. Archive of International Medicine, 162(22), p. 2527-2536. Smith, J.P., Stone, R.W. and Muschenheim, C. (1968) Acute respiratory failure in chronic lung disease. American Review of Respiratory Disease, 97(5), p. 791-803. Stevenson, N.J., Walker, P.P., Costello, R.W., and Calverley, P.M. (2005) Lung mechanics and dyspnea during exacerbations of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine, (172), p. 1510–1516. Vermeeren, M.A., Schols, A.M. and Wouters, E.F. (1997) Effects of an acute exacerbation on nutritional and metabolic profile of patients with COPD. European Respiratory Journal (10), p. 2264–2269.

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