Alcoholism case study Notes

Topics: Liver, Hepatocyte, Bile Pages: 1 (225 words) Published: December 5, 2014
Liver function test
Low LFTs indicate low probability of significant diseases
Abnormal results provide info in the identifications of the type of liver disease. Provide info on the prognosis of the patient, in particularly the survival time in both chronic and acute disease Bilirubin concentration – normal production in adult is 450 µmol per day Normal concentration – less 20 µmol/L

Abnormal concentration – above 50 µmol/L
Injection of thiamine (vitamin B1)
Mallory bodies – an acumination of eosinophilic material in the cytoplasm of damaged liver cells in certain forms of cirrhosis. Polymorphnuclear – white cells of the blood that have a nucleus of an irregular and varied shape. Form 70-70% of all white cells. Micronodular – presence of small nodules that have somewhat coarser appearance than granular tissue Hepatocyte (Parenchymal cells) – the main cell type in the liver. A large cell that is important for the metabolic function including: synthesis and storage of biochemical products; detoxification of poisons and unwanted substances; and the manufacture of bile. Jaundice

yellow discolouration of tissues due to the accumulation of bilirubin concentration of bilirubin on serum is over 50 µmol dm-3 (Ahmed, N. et al. 2006) Ahmed, N., Dawson, M., Smith, C., Wood, E., (2006). Biology of Disease, United Kingdom: Taylor & Francis, Inc. Marcovitch, H., (2009). Black’s Medical Dictionary, United Kingdom: A & C Black Publishers Ltd.
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