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Homeostasis

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Homeostasis
HOMEOSTASIS
GROUP 5
RESEARCHERS
MUNASHE MUDUMISO R136670X TAWANDA CHIKUKUZA R136602Y JOHN MTINIWA R136553H LEARNMORE SHOTI R136619N WELLINGTON CHIPADZE R113616B MASIMBA

Homeostasis is the ability to maintain a stable internal body environment in an ever changing outside world. It can also be said to be the body’s attempt to maintain a relatively constant internal environment in the face of constantly changing external conditions. Homeostasis is used by physiologists to define maintenance of nearly constant in the internal environment. Chemical, thermal and neural factors interact to maintain homeostasis. Feedback controls distributed around the body help maintain the vital balances needed to maintain body function. The maintenance of constant conditions is achieved by the coordination of all the organs and tissues. In the body positive, negative and feed-forward feedback mechanisms occur. Generally to maintain homeostasis the body uses the negative feedback mechanisms.There is a general homeostatic mechanism. It involves disruptors or stimuli, detectors or sensors, control system, efferent pathway and effectors. Certain disruptors produce a change in variable. The sensors sense the change. The information about the change is then sent to the control system via the afferent pathway. From the control system there is output. The information concerning the output is sent along efferent pathway to the effectors. The effectors then respond and influence the degree to which the stimuli restore the affected variable to homeostasis. Examples of homeostatic control systems CELL VOLUME HOMEOSTASIS All cells face a critical problem in the maintenance of a constant volume in the face of extracellular and intracellular fluctuations. These fluctuations can result in cell volume increase or decrease. These are generally swelling and shrinkage respectively.



References: * Cellular volume homeostasis Advan Physiol Educ 28:155-159, 2004. doi:10.1152/advan.00034.2004 Kevin Strange * Ganong’s Review of Medical Physiology 23rd Edition .Textbook of Medical Physiology 11th Edition, Guyton & Hall

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