Cell Bio
BIO 353 Cell Biology Study Questions for Exam #3 Fall, 2012
Cytoskeleton
“The harder the conflict, the more glorious the triumph.”
Thomas Paine... “Unless you really just screw up.” Bush
1. What are microfilaments?
(He said know how to identify/draw these) Note: since it is multiple choice, I doubt we will have to know how to draw them. **There are also short essay questions and, in past classes, he has asked students to draw. I thought the final was ALL MULTIPLE CHOICE???********************************
Microfilament- Analogous to actin microfilaments. Helical polymer of actin protein; two protofilaments. Smallest cytoskeleton diameter (3-6nm) structure Thinner, shorter, more flexible than microtubes. One basic 7subunit, globular actin. Structurally polar. Have fast reaction to stimuli.
What super structures do they form?
1.Microvilli; structure of microfilaments lining the edge of cell
2.Stress fibers; antiparallel of actin bundles, contractile forces, wound healing ect.
3.Lamellipodia; sheet lik1.Nucleating proteins; Arp2/3 ce projections for movement, actin bundles parallel to cell surface- Same category as Filopodia
4.Filopodia; hair-like extensions or movement and sensory
5.Contractile ring; to help split cells
What other proteins do actin and microfilaments interact with? * complex help in nucleation of microfil., polymerization/ depolymerization, interaction with cell components
What kinds of microfilamentous structures does each protein help form? 1. Bundling protein; F-actin is org. into diff. assemblies based on cross linking proteins 1. Contractile Bundles- Associated protein-Myosin 2 that always moves to + end of F-actin, Non-structurally polar (even tho F-actin is polar by itself), Function-contractions, motility, ect., examples- stress fibers, contractile ring 2. Non-Contractile Bundles- Arranged in tight bundles and sheets, Structurally polar. Formed at the cell’s surface. Increase surface area.
Cytoskeleton
“The harder the conflict, the more glorious the triumph.”
Thomas Paine... “Unless you really just screw up.” Bush
1. What are microfilaments?
(He said know how to identify/draw these) Note: since it is multiple choice, I doubt we will have to know how to draw them. **There are also short essay questions and, in past classes, he has asked students to draw. I thought the final was ALL MULTIPLE CHOICE???********************************
Microfilament- Analogous to actin microfilaments. Helical polymer of actin protein; two protofilaments. Smallest cytoskeleton diameter (3-6nm) structure Thinner, shorter, more flexible than microtubes. One basic 7subunit, globular actin. Structurally polar. Have fast reaction to stimuli.
What super structures do they form?
1.Microvilli; structure of microfilaments lining the edge of cell
2.Stress fibers; antiparallel of actin bundles, contractile forces, wound healing ect.
3.Lamellipodia; sheet lik1.Nucleating proteins; Arp2/3 ce projections for movement, actin bundles parallel to cell surface- Same category as Filopodia
4.Filopodia; hair-like extensions or movement and sensory
5.Contractile ring; to help split cells
What other proteins do actin and microfilaments interact with? * complex help in nucleation of microfil., polymerization/ depolymerization, interaction with cell components
What kinds of microfilamentous structures does each protein help form? 1. Bundling protein; F-actin is org. into diff. assemblies based on cross linking proteins 1. Contractile Bundles- Associated protein-Myosin 2 that always moves to + end of F-actin, Non-structurally polar (even tho F-actin is polar by itself), Function-contractions, motility, ect., examples- stress fibers, contractile ring 2. Non-Contractile Bundles- Arranged in tight bundles and sheets, Structurally polar. Formed at the cell’s surface. Increase surface area.