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Cell Anatomy - Microbodies

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Cell Anatomy - Microbodies
CELL ANATOMY
Microbodies

Brief History
Microbodies were first discovered and named in 1954 by Rhodin. De Duve chose the name of Peroxisome because of its relationship with hydrogen peroxide. In 1967, Breidenbach and Beevers were the first to isolate microbodies from plants, which they named Glyoxysomes because they were found to contain enzymes of the Glyoxylate cycle.
Definition
Any of the membrane-bound, ovoid or spherical, granular cytoplasmic particles containing enzymes and other substances, which originate in the endoplasmic reticulum of vertebrate liver and kidney cells and other cells, and in protozoa, yeast, and many cell types of higher plants.
Avarage Size
0.2 - 1.5 micrometers in diameter
Function
Microbodies contain enzymes that participate in the preparatory or intermediate stages of biochemical reactions within the cell. This is the breakdown of fats, alcohols and amino acids.
Peroxisome and Glyoxysomes
Peroxisome
A peroxisome is a type of microbody that functions to help the body break down large molecules and detoxify hazardous substances. It contains enzymes like oxidase, which can create hydrogen peroxide as a byproduct of its enzymatic reactions. Within the peroxisome, hydrogen peroxide can then be converted to water by enzymes like catalase and peroxidase.
Glyoxysomes
Glyoxysomes are specialized peroxisomes found in plants and mold, which help to convert stored lipids into carbohydrates so they can be used for plant growth. In glyoxysomes the fatty acids are hydrolyzed to acetyl-CoA by peroxisomal β-oxidation enzymes. Besides peroxisomal functions, glyoxysomes also possess the key enzymes of the Glyoxylate cycle.
Location
Microbodies can be found in the cells of plants, protozoa, and animals.
Microbodies are mostly found in livers and kidney organs for vertebrates.
Reporduction
Microbodies also do not contain any genetic material that allows them to reproduce.
Origin

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