The series of events prompting muscle contraction is started some place in the central nervous system‚ either as willful action from the brain or as reflex action from the spinal cord. Beginning with depolarization at the neuromuscular junction‚ the depolarizing impulse discharges acetylcholine from the nerve ending. Which then diffuses over the neuromuscular junction (a chemical synapse formed by the contact between a motor neuron and a muscle fiber). At the motor end plate‚ the acetylcholine joins
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There are three phases for muscle cell contraction: initiation of action potential in the sarcolemma‚ excitation-contraction coupling‚ and contraction‚ sliding of the myofilaments. ATP and calcium ions are two essential elements for muscle contraction. When ATP attaches to the myosin head‚ it gets hydrolyzed to ADP and Pi. Calcium ions bind to the troponin molecules and help expose the binding sites of actin filaments to allow for the attachment of the myosin heads. After the sliding of the myofilaments
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Biochemistry of Muscle Contraction Fred P. Guillergan M.D.‚ FPCP Outline histology and biochemistry of muscles (Striated & smooth) – Myosin – Actin‚ Tropomyosin‚ Troponin – Accessory proteins of muscles Biochemical events in muscle contraction Calcium‚ Ca2+-binding proteins and Ca2+ channels in muscle contraction Biochemistry of Cardiac & Smooth muscle contraction Energetics of muscle contraction ☻Able to understand the normal anatomy and physiology of different types of muscles ☻ Provide
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Skeletal muscle is a voluntary and striated muscle that attaches to the skeleton to allow control over posture and movement. Each skeletal muscle consists of bundles of muscles fibers called fascicles. These fascicles are composed of many individual muscle fibers or muscle cells that can be up to several millimeters long. These muscle fibers are composed of myofibrils‚ which are organized into thick filaments‚ myosin‚ and thin filaments‚ actin. These filaments are organized into repeating structures
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for muscle contraction. Hypothesis: Based off the frog muscle immersed separately in Solution A of ATP and distilled water solution‚ Solution B of ATP with KCl in distilled water and MgCl2 in distilled water and solution C of KCl and MgCl2 in distilled water‚ I hypothesize that solution B of ATP with KCl in distilled water and MgCl2 in distilled water will cause the muscle to contract. Introduction: This lab consisted of discovering what solutions will cause a muscle to contract. A muscle contraction
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Nutrition A Muscle Contraction Muscle Contraction is part of an organ in the body that is tensive. It may have a process of tensions that may be developed with muscle tissues. Contraction can be a meaning of shortening or long. Muscle Contraction can also produce a muscle cell that is for movement of the body. Myosin and Actin is an interaction protein to Muscle Contraction‚ it can be changed by shape but not by volume. Skeletal Muscle contraction is produce by heat. The muscles may receive signal
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Muscle contractions tend to be smooth and vary in strengths‚ depending on the demands placed on them. The variations of strength are called graded muscle responses. There are two ways a muscle contraction can be graded‚ either by changing the frequency of stimulation or by changing the strength of the stimulation. When a muscle is responding to a change in stimulus frequency‚ the nervous system will reach a greater muscular force when increasing the firing of motor neurons. This causes a wave or
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During a Muscle Contraction The muscle fiber is in a resting state. The resting state is slightly negative inside and slightly positive outside. It has to be in this state in order to receive a message. First the brain sends a message to the muscle using a neuron then reaches the axon terminal of the neuron. Calcium gates then open on the axon terminal allowing calcium to rush in. Ach release from axon terminals‚ diffuses across the synaptic clef and binds to (receptors) on motor end plate. Then
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an involuntary muscle‚ found solely in the walls of the heart‚ as well as in the walls of the blood vessels. This sort of muscle has similarities with the skeletal muscles‚ because it is striated. Furthermore‚ it has slight similarities to the smooth muscles‚ because its contractions are not under conscious control. On the other hand this type of muscle is highly specialised. It is under the control of the autonomic nervous system‚ however‚ even without nervous imput contractions can occur due to
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Muscle Contraction & Excitation Muscle excitation takes place when there is a synaptic transmission and induction of an impulse. There are six steps that take place during muscle excitation. (1)The action potential travels down the somatic motor neuron axon reaching the synaptic bulb causing calcium ions to flow into the synaptic bulb. (2)The increase of calcium in the synaptic bulb causes the synaptic vesicles to undergo exocytosis. (Exocytosis a process that allows large molecule to leave
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