What is Gamma-Hydroxybutyrate? It is also known as the GHB, and is a central nervous system depressant. GHB can be found in different forms like clear liquid, white powder, tablet, and capsule forms.(Moore, and Measham 565-590) It is very dangerous because GHB is odorless and colorless with a salty taste and when it is in a liquid form it is virtually impossible to be detectable.(O’Connell, and Kaye) This drug can found available by prescription for treating sleep disorders. GHB can also be made in homes because many of the substances are commonly used as drain cleaners and floor stripping solvents.(Moore, and Measham 565-590) GHB was first developed to prevent pain, but did not work so well so its use as an anesthetic declined. Research is being conducted for the use of Narcolepsy; in which people have trouble staying awake; people with Narcolepsy fall in the middle of activities that produce strong emotions.(Tunnicliff, and Toxicol 581-590) “GHB can also be produced normally in the brain through the synthesis of a neurotransmitter called GABA; some of the greatest concentrations of GHB are found in the substantia Ingra, thalamus and hypothalamus.”(Tunnicliff, and Toxicol 581-590) GHB can reduce dopamine activity, especially in the basal ganglia. The release of dopamine from synaptic terminal is probably the result of the inhibition of synaptic terminals.(Tunnicliffy, and Toxiol 581-590) Gamma-Hydroxybutyrate was once legal and sold in the United States Food and Drug Administration for over the counter sales for bodybuilders. “President Clinton signed the federal legislation making the possession of GHB illegal.”(Tunnicliff, and Toxicol 581-590) It was schedule as III control substance; that can be used for medical purposes, but it cannot be sold, distributed or provided to anyone other than for its prescribed used.(Tunnicliff, and Toxicol 581-590) Gamma-Hydroxybutyrate is abused in different forms, but the most common abusers are body...
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