Thesis: the Diuretic Activity of Fresh Balloonvine Leaves

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  • Topic: Mouse, Diuretic, Scientific control
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The Diuretic Activity of the Fresh Balloonvine (Cardiospermum halicacabum Linn) Leaves Extract
RESEARCHERS
Arapoc, Kevin Ross
Flores, Van Giovanni
Jondonero, Graselle
Navarro, Charizze
Serafino, Cherry Lou

A Research Project Presented to the Science Department of South Philippine Adventist College (SPAC) as Partial Fulfillment of the Requirements for the course Science IV (Physics)

Mr. Ranzolin G. Bayeta
Adviser

South Philippine Adventist College
Camanchiles, Matanao, Davao del Sur

February 25, 2011

ABSTRACT
This study was conducted to know the diuretic activity of the extract of the balloonvine (Cardiospermum halicacabum L.) leaves.
In this study, three groups were used. These includes the positive control group (furosemide 20mg/2ml), experimental group (balloonvine leaves extract), and the control group (water treated).
The fresh leaves of balloonvine were extracted by pounding the leaves and then squeezed using a clean cloth. The mice were also weighed to determine the allowable dosage according to its weight. After the preparation of the groups, 3 trials were conducted. In the first trial, furosemide (positive control) has the most volume of urine, followed by the balloonvine leaves extract (experimental group) and the control group, which is the water treated has the least volume of urine. The next two trials have the same results as of trial 1. This means that furosemide is still the best diuretic drug but balloonvine leaves extract can also be used as a substitute since it has excreted more volume of urine than of the water treated group (control group) but not as good as the furosemide do.

The researchers recommend further studies using other parts of the plant and using higher concentration to prove whether balloonvine can be more effective if used in higher dosage and to have more investigation of the plant.

Acknowledgment

The researchers would like to express their sincere gratitude to those who helped them finished this project. Their parents for the financial support, moral support and understanding. They contributed a lot to finish this project. Mrs. Sharon Meriales for the advices and the help se extended to the group. The Jhing2 printing press for the printing and discounts.

To our physics teacher and adviser, Sir Ranzolin Bayeta, for the suggestions, encouragements and teachings he shared and to our Almighty Heavenly Father who gives us the knowledge, wisdom and strength to finish this study.

Thank you!

TABLE OF CONTENTS

Title page…………………………………………………………………………………………………………………………….i Abstract……………………………………………………………………………………………………………………………...ii Acknowledgment…………………………………………………………………………………………………………….….iii Table of Contents……………………………………………………………..…………………………………………….….iv Chapter 1 Introduction………………………………………………………………………………………………….……1

Background of the study……………………………………………………………………………….……1
Statement of the problem………………….……………………………………………………………….2
Significance of the study……………….…………………………………………………………………….3
Scope and limitations…………….….…………………………………………………………………………4 Chapter 2 Review of related literature.……………………………………………………………………………….5 Chapter 3 Methodology…………………….………………………………………………………………………………..10 Chapter 4 Results and discussion….…………………………………………………………………………………….14 Chapter 5 Summary, conclusion, and recommendation…….……………………………………………....18 Bibliography………………………………………… ……………………………………………………………………….…..20

Chapter I
Introduction
Background of the Study
In this natural world, lots of efforts were made by the people to achieve a better quality of life and for man’s survival. A lot of people were making alternatives and medicine for the health of the mankind. Plants are commonly used by people to cure many diseases for many years.

Nowadays, medicines are very expensive and because of that, the less fortunate ones cannot afford to buy some. Because of that, they can use herbal medicines as an alternative drug. God provided many...
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