The Disordered Brain

The episode of the disordered brain explored different neurological diseases, touched a little bit on their mechanisms, genetics in disorders, currently used and future potential treatments. It also identified the difference between neurobiological and psychiatric disorders being the nature of symptoms and the anatomical location of damage. One of their fundamental differences is that the neural circuit responsible for most psychiatric disorders is not known while there is a good insight to the circuitry responsible for most neurobiological disorders. The group of scientists that were featured on this episode have worked on the brain in an effort to develop repair for the sick brain. Their work revolved around Parkinson’s disease, Stroke, Huntington’s disease and Spinal cord injury. They did mention that these disorders gave more insight to the brain than any other disease. Movement was learned through Parkinson’s disease, speech through stroke and the link between thoughts and actions through spinal cord injury.

The progress to revolutionized treatments was possible because of the knowledge of the location of specific neurobiological disorders. The contribution of Broca and Wernicke was also noticed as a stepping stone to understanding the localization of functions, in their case, language. Their study encouraged the discovery of the locations that are involved in movements. Mahlon Delong talked about basal ganglia and its role in movement. He mentioned that a restricted part of the basal ganglia is devoted to movement and the rest to higher functions. He identified the basal ganglia being the control of movement in Parkinson’s disease by a method that involved putting a lesion to a small motor circuit within the basal ganglia. I appreciated the deep brain stimulation for treatment of Parkinson’s disease that he worked on. He mentioned that this method is advantageous because it is a non destructive, a reversible and an adjustable... [continues]

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