Syphilis: History and Diagnosis

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What is the difference between a disease and a bacterial disease? - A bacterial disease doesn't need a host, it is able to reproduce without outside influence. Virii can't do this, they require a host. Virii also target specific cells, unlike bacteria. [1]

Specifics about Syphilis: Syphilis is a bacterium spread by intercourse, making it a STD. [3]Syphilis is specifically is a spirochete bacteria, Teponema pallidum. T. pallidum is a fragile spiral bacterium 6-15 micrometer long by 0.25 micrometers in diameter. Undetected by light microscopy, it can only be ifentified by a distinctive undulating movement on a darkfield microscopy. T.pallidum can only survive ina short period on the body. The infection of syphilis is classified into 4 stages: primary , secondary, latent, and tertiary [3]. T. pallidum is transmited through the mucous membranes or open skin-to-skin contact, primily sexual intercourse. It can also be transferred through blood transfusion. After infection, it begins an incubation period, entering the lymphatic system, bloodstream, and soon after disseminates from the point of contact. A chancre ( A painless ulcer, particularly one developing on the genitals as result of a veneral disease. [2]) forms at the site of inoculation. This chancre spontaneously heals in a two to eight week period, but then then the infected enters the secondary stage of syphilis. If the infected has an intact immune system the disease will enter a period of latency. After the period of latency, which can last four or more years in someone un(der)treated individual, gummas are formed that cause dysfunction in any organ system. Gummas are what also account for the dysfunction found in tertiary syphilis. If left untreated, it can cause dysfunction of the central nervous and cardiovascular system which can lead to progressive dementia and death.

The History of Syphilis: Studies have foung that syphilis is a disease of early time, and could have been prevalent among the...
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