October 22, 2012
In this study, we will evaluate the role of malaria in a patient with sickle cell anemia and how it is a protection. Sickle cell is a hereditary disease where by parents that possesses the trait passes it on to their offspring through genes. Sickle cell anemia is mostly common in Africa particularly in children under the age of five. Although sickle cell can be beneficial in some ways but it can also be dangerous. We shall elaborate more in this study how a sickle cell patient can be immune to severe malaria.
Sickle cell anemia and malaria in Nigeria
Populations all over the world mostly Africans- suffer from the disease sickle cell anemia. Anemia is said to be a situation whereby the concentration of hemoglobin is low in the red blood cell of an individual. It is also said to be the most common blood disease. While some people are born with normal traits or alleles, others are born with the sickle cell trait or sicklemia which is when an individual has an abnormal allele in the hemoglobin beta gene. Sickle cell disease is a severe condition in which the body is producing abnormal hemoglobin in the red blood cells. Sickle cell disease is a disease that is inherited from one’s parents; the two parents involved must possess the trait to pass it on to their offspring. Individuals who are born with normal genes inherit two copies of the protein (beta) gene, and they are said to have the AA genotype, while those who have sickle cell traits have the AS genotype. The S in the sickle cell genotype comes from both parents, which makes the red blood cells of individuals with sickle cell disease turn into a curved shape known as sickled shape. In Nigeria, when two parents have the AS genotype, they tend to have a child with the sickle cell disease and may have one with one recessive allele. The article “Sickle Cell Anemia” explains that there are seven different...