Seperating and Extracting Components of Panacetin

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Seperating and Extracting the Components of Panacetin

Aim: To measure, analyze, through extraction and seperation of the components of chemical, Panacetin, which will conclude whether the label attached measures adequate amounts and contains US grade safe contents to which the drug, Panacetin, is originally produced by. Extraction of the chemicals Sucrose, Aspirin, and an Unknown substance is tested to determine the legitimacy of the label and drug.

Theory: The percent composition is calculated for accuracy and to conclude the “label is accurate”. The formula for the percent composition is adding the sums of all the extracts, then dividing the total sum by each of the three (3) individual extract; Sucrose, Aspirin, Unknown. By separating and extracting the three (3) substances from the original drug, Panacetin, analysis can conclude whether it has been smuggled from overseas, which contains toxins, or has been made inside the US, with USP orders and specifications.

Materials: The materials used for this experiment are a 15 mL centrifugation tube and cap to add 0.40 g of the drug, Panacetin, and a graduated cylinder to measure 8.0 mL of dichloromethane, and filter paper. A digital scale, a centrifuge, two (2) test tubes, 4.0 mL of 5.0% NaHCO3, micropipette (glass with rubber suction top), a stirring rod, and a vial. A 50 mL beaker, 2 x 1.0 mL of 6.0 M HCl, pH paper, a vacuum chamber, a test tube rack, scooper, ice bath, hot water bath, hot plate, Hirsche funnel, and a rubber tube are all necessary to perform the experiment.

Method: Weigh and add 0.40 g of Panacretin to a 15.0 mL centrifuge tube with a rubber stopper. Add 8.0 mL of dichloromethane to the 0.40 g of Panacretin and shake thoroughly, then place in a centrifuge, at three (3) speed for three (3) minutes. Extract the Sucrose and weigh using a digital scale (must be tared for accuracy). Separate the 8.0 mL of DCM to two (2) test tubes, each containing 4.0 mL of DCM. Add 4.0 mL of NaHCO3...
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