Role of Ammonia in Hepatic Encephalopathy: Double Blinded Case Study for Stats

Topics: Liver, Hepatic encephalopathy, Cirrhosis Pages: 3 (779 words) Published: March 3, 2013
Role of Ammonia in Hepatic Encephalopathy|
Anastasia Kepler|

Math 15 Todd Olsen Tues, Thurs, Friday |

The human liver is truly amazing, however little is ever said about the organ. Most people probably wouldn’t be able to locate their liver if they’re asked to do so. The second largest organ in the body and weighing about 3 pounds, the liver is located right under your rib cage on the right side of your body. It is the only organ that is able to regenerate. While most organs replace damage with scar tissue, the liver has the ability to replace damaged tissues with new cells. The primary function of the liver is to process food that has been consumed into nutrients and filter out any harmful substances that may be the bloodstream. The liver is responsible for keeping our blood suitable for our bodies. With that understood it saddens me to say that there is an estimated 30 million people living in the U.S. with liver failure. These 30 million people are unable to filter out any harmful toxins that may be flowing in their bloodstream. With time they may began to suffer from Hepatic Encephalopathy. Described as episodes of confusion and altered levels of consciousness Hepatic Encephalopathy is caused by to an accumulation of ammonia in the bloodstream that would usually be filtered out by the liver. Although Hepatic encephalopathy is completely reversible with treatment there are very few treatments available. Pharmaceutical have saved many lives through experimental studies and treatments. Although very controversial; many people choose to participate in these studies in hopes of increasing their chances to live a normal life despite suffering from an ailment. I chose to do my assignment on a double-blinded study on the use of Glycerol Phenylbutyrate (also known as Ravicti) in patients with Episodic Hepatic Encephalopathy.

The study was completed by Dr. Don Rockey who is the Chief of Medicine at the Medical University of...
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