Research Paper On Creatinine

Serum creatinine is an important marker of renal health as it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the kidneys. Creatinine itself is produced by a biological system include creatine, phosphocreatine or creatine phosphate, and adenosine triphosphate “ATP”.
Creatine is formed mainly in the liver from the methylation of glycocyamine by S-adenosyl methionine. It is then carried through blood to the other organs, muscle, and brain, where, through phosphorylation, it becomes the high-energy compound phosphocreatine. Creatine transformation to phosphocreatine is activates by creatine kinase; spontaneous formation of creatinine produces throughout the reaction. As shown in (fig. 15)
Creatinine is removed