Polio Vaccine

Topics: Polio vaccine, Poliomyelitis, Vaccine Pages: 3 (1051 words) Published: December 20, 2012
Poliomyelitis (Polio) is an acute viral disease, usually affecting children and young adults, caused by any of three polioviruses, characterized by inflammation of the motor neurons of the brain stem and spinal cord, and resulting in a motor paralysis, followed by muscular atrophy and often permanent deformities. Polio (infantile paralysis) is a disorder caused by a viral infection that affects the whole body, muscles, and nerves. If not treated quickly it could cause permanent damage or even in the most severe cases, death. This virus is transmitted from person to person by fluids that come out of the mouth or nose. Once it is transferred it multiplies in the throat and intestinal tract and then spreads to the blood. There is still no actual cure for this crippling virus. Our president Franklin Delano Roosevelt became ill with Poliomyelitis. He was paralyzed from waist down, causing him to be crippled. Roosevelt was the founder of the March of Dimes. As the leader of the March of Dimes organization, Franklin tried to quickly respond to polio epidemics in the nation, and fine it affordable to get children vaccinated. In 1952 Dr. Jonas Salk was the first to come up with the first polio vaccine, the IPV (Inactivated Polio Vaccine). In 1947 Salk became head of the Virus Research Lab at the University of Pittsburgh. He began investigating the poliovirus. One of the hardest things about working with poliovirus was manufacturing enough to experiment with and to make vaccine production practical. To start with, he had to sort the 125 strains of the virus. He found that they fell into three basic types and knew that a vaccine would have to include these three types to protect against all polio. The vaccine is a clear, colorless sterile suspension for subcutaneous injection. IPV contains strains of the 3 types of polioviruses (Types 1, 2, and 3), originally grown in monkey kidney cell culture and inactivated by exposure to formaldehyde. Salk’s vaccine efficiently...
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