Physioex 8.0 Exercise 10

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Exercise 10: Acid/Base Balance Worksheet
Assignment Due: Week 1

Student instructions: Follow the step-by-step instructions for this exercise found in your text and record your answers in the spaces below. Submit this completed document by the assignment due date found in the Syllabus.

Please make sure that your answers are typed in RED.

Please type your Name and Student ID Number here: Stephanie Brewer 4189660

Activity 1: Normal Breathing

1. At 20 seconds, pH = 7.41
2. At 40 seconds, pH = 7.41
3. At 60 seconds, pH = 7.41
4. Did the pH level of the blood change at all during normal breathing? If so, how? No.
5. Was the pH level always within the “normal” range for the human body? Yes.
6. Did the PCO2 level change during the course of normal breathing? If so, how? No, the level stayed steadily at 40mm.

Activity 2a: Hyperventilation – Run 1

1. At 20 seconds, pH = 7.45
2. At 40 seconds, pH = 7.53
3. At 60 seconds, pH = 7.67
4. Maximum pH =7.68
5. Did the pH level of the blood change at all during this run? If so, how? Yes, the pH level of the blood increased.
6. Was the pH level always within the “normal” range for the human body? If not, when was the pH value outside of the normal range, and what acid/base imbalance did this pH value indicate? No, at 40 seconds the pH value indicated alkalosis.

7. Did the PCO2 level change during the curse of this run? If so, how? Yes, the Pco2 level decreased significantly.
8. If you observed an acid/base imbalance during this run, how would you expect to renal system to compensate for this condition? Increasing H+ absorption by increasing HCO3 secretion. 9. How did the hyperventilation trace differ from the trace for the normal breathing? Did the tidal volumes change? The trace was erratic and the tidal volume increased to approximately 3 liters. 10. What might cause a person to hyperventilate?

Fever or anxiety can cause hyperventilation.

Activity 2b: Hyperventilation – Run 2

1. What happened to the trace after the 20-second mark when you stopped the hyperventilation? Did the breathing return to normal immediately? Explain your observation. When I stopped the hyperventilation at the 20-second mark breathing completely stopped for approximately 7 seconds, then began again at a normal rate.

Activity 3: Rebreathing

1. At 20 seconds, pH = 7.35
2. At 40 seconds, pH = 7.29
3. At 60 seconds, pH = 7.24
4. Did the pH level of the blood change at all during this run? If so, how? Yes, the pH level of the blood decreased.
5. Was the pH level always within the “normal” range for the human body? If not, when was the pH value outside of the normal range, and what acid/base imbalance did this pH value indicate? No, acidosis occurred at 40 seconds when the pH dropped out of “normal” range to 7.29. 6. Did the PCO2 level change during the course of this run? If so, how? Yes, the Pco2 level elevated.

7. If you observed an acid/base imbalance during this run, how would you expect the renal system to compensate for this condition? Increasing HCO3-, excreting more H+ to balance the pH of the blood. 8. How did the rebreathing trace differ from the trace for normal breathing? Did the tidal volumes change? Rebreathing trace had a larger gap between the varying high and low points. Normal breathing it was approximately 2.5-3 liters, whereas rebreathing was approximately 2.-3.5 liters. 9. Give examples of respiratory problems that would result in pH and PCO2 patterns similar to what you observed during rebreathing? Airway obstruction, depression of the respiratory center in the brain stem, lung disease and drug overdose can all acidosis.

Renal System Compensation
Activity 4: Renal Response to Normal Acid/Base Balance

1. At normal PCO2 and pH levels, what level of H+...
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