the process by which amino acids are linearly arranged into proteins through the involvement of ribosomalRNA, transfer RNA, messenger RNA, and various enzymes.
Before the synthesis of a protein begins, the corresponding RNA molecule is produced by RNA transcription. One strand of the DNA double helix is used as a template by the RNA polymerase to synthesize a messenger RNA (mRNA). This mRNA migrates from the nucleus to the cytoplasm. During this step, mRNA goes through different types of maturation including one called splicing when the non-coding sequences are eliminated. The coding mRNA sequence can be described as a unit of three nucleotides called a codon.
The ribosome binds to the mRNA at the start codon (AUG) that is recognized only by the initiator tRNA. The ribosome proceeds to the elongation phase of protein synthesis. During this stage, complexes, composed of an amino acid linked to tRNA, sequentially bind to the appropriate codon in mRNA by forming complementary base pairs with the tRNA anticodon. The ribosome moves from codon to codon along the mRNA. Amino acids are added one by one, translated into polypeptidic sequences dictated by DNA and represented by mRNA. At the end, a release factor binds to the stop codon, terminating translation and releasing the complete polypeptide from the ribosome.
Terms | Definitions |
Introduction | The beginning of the story where the characters and the setting is revealed. |
Rising Action | This is where the events in the story become complicated and the conflict in the story is revealed (events between the introduction and climax). |
Climax | This is the highest point of interest and the turning point of the story. The reader wonders what will happen next; will the conflict be resolved or not? |
Falling action | The events and complications begin to resolve themselves. The reader knows what has happened next and if the conflict was resolved or... [continues]
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