Topics: Thyroid hormone, Thyroxine, Hypothyroidism Pages: 2 (337 words) Published: December 12, 2012
Steven Johnson Syndrome/ Prednisolone Oral

Description: This is a rare serious disorder that your skin amd mucous membranes which they react relentlessly to medication or infection. This begins with will you having flu like symptoms, then you have painful red or purplish rash that spreads and turns into blisters before the top layer of your skins sheds. Signs and Symptoms:

* Hives
* Painful Skin
* Swelling of the tongue
* Swelling of the Face
* Cough
* Burning Eyes
* Sore Throat
Etiogly: One of factors that contribute Hypothyroid such as genetics and environmental factors. Incidence: There are about 300 people in the United States that are diagnoses each year with this disease. Diagnosis: This can be diagnosis if a person has either herpes simplex virus. Treatment: Medication and Skin Grafting are two different forms of treatment. Prognosis: This has a mortality rate of around 5%

Preventive Measures: This is genetc so there are no preventive measures.

Prednisolone Oral Lithium
Schedule & Pregnancy Category: This is a Category A drug. Available as: Synthroid, Thyrax, Euthrax
Indications: This is also a replacement for the thyroid gland and supplemental therapy in congenital hypothyroid. Mechanics of Action: This acts like the endogenous thyroid hormone thyroxine. The liver and the kidney the T4 is converted into an T3 metabolite. Pharmacokinetics: Major hormone secreted from thyroid gland. Thyroxine released from the thyroglobin by proteolysis and secreted in the blood. Side Effects: The symptoms that should be monitored very closely are a gain of appetite, stomach pain. Adverse Reactions: Eye Hemorrhage, Oral Discomfort, Tooth Loss and Bone Lesion. Contraindication: Untreated adrenoctical failure and acute cardiac infraction. Toxicity: Hypermetabolic state in distinguishable from thyrotaxicosis of the endogenous. References:

Nirken MH, et al. Stevens-Johnson syndrome and toxic epidermal necrolysis:...
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