There are numerous anti-infective medications available, and sometimes a combination of drugs must be given to rid the infection. Regardless, most infections can be controlled and removed. The anti-infective medication highlighted in this paper will be cefazolin better known as Ancef. Cefazolin is a member of the cephalosporins. According to Lilley, Rainforth-Collins, Harrington & Snyder, 2011, “Cephalosporins are semisynthetic antibiotics widely used in clinical practice. They are structurally and pharmacologically related to the penicillins. Like penicillins, cephalosporins are bactericidal and work by interfering with bacterial cell wall synthesis. They also bind to the same penicillin-binding proteins inside bacteria” (p.594).
Indications and Usage:
Upper, lower respiratory tract, urinary tract, skin infections; bone, joint, biliary, genital infections; endocarditis, surgical prophylazis, septicemia (Skidmore, 2011).
CNS- headache, dizziness, weakness, paresthesia, fever, chills, seizures (high doses) GI- nausea, vomiting, diarrhea, anorexia, pail, glossitis, bleeding; increased AST, ALT, bilirubin, LDH, alkaline phosphatase; abdominal pain, pseudomembranous colitis GU-proteinuria, vaginitis, pruritis, candidiasis, increased BUN, nephrotoxicity, renal... [continues]
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