• The new extended macrolide group (clarithromycin, azithromycin, dirithromycin) has been effective in treating numerous organisms because they have a longer half life than erythromycin. • Erythromycin is not given IM! too painful for the patient • Adverse reaction of Azithromycin is hepatotoxicity or liver impairment. Liver function test must be monitored. • Most notable side effect of tetracycline is teeth discoloration. It is prescribed for URTI and LRTI • Super infection is a side effect of many antibacterials, including tetracyclines, especially when they are administered in high doses because the drug disrupts the microbial flora of the body.
• Effect of oral contraceptives are decreased by tetracycline. And should be taken on an empty stomach. • Side effect of Gentamycin is decreased urinary output.
• Aminoglycosides may cause hearing loss.
• Fluoroquinolones, such as ciprofloxacin (Cipro), are commonly prescribed antibiotics. These agents are primarily given to treat lung infection
• A nurse is aware that crystalluria is a common problem with sulfonamides. To remedy this px has to increase fluid intake. They are commonly prescribed for UTI and ear infections • Trimethoprim prevents bacterial resistance to sulfamethoxazole. Half life is 8-12 hours. Side effect is Neutropenia and agranulocytosis
• ANTITUBERCULAR DRUGS, ANTIFUNGAL DRUGS,
• PEPTIDES, AND METRONIDAZOLE
• History and occurrence
• Diagnostic measures
• Antitubercular drugs
• Prophylactic antitubercular drug therapy
• Clients at risk
• Drug selection(s)
• Antitubercular Drugs
• Drug combinations for antitubercular drug therapy
• Record keeping of daily antitubercular drugs
• First-line antitubercular drugs
• Isoniazid, rifampin, rifabutin, pyrazinamide, ethambutol, streptomycin • Antitubercular Drugs (cont’d)
• Second-line antitubercular drugs
• Kanamycin, cycloserine, capreomycin,...
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