Organic Chemistry II Laboratory manual 
Organic Chemistry II Laboratory
(ABCT357/ABCT3757)
Lab Manual
2014-2015
Lee Hang Wai, Alston
(alston.lee@polyu.edu.hk)
Dr. Lee Cheng Hao, Samuel
(chenghao.lee@polyu.edu.hk)
Organic Chemistry II Laboratory (ABCT357, ABCT3757) (Group one)
Contact: Alston Lee (alston.lee@polyu.edu.hk)
Tuesday 8:30-11:30 , Laboratory: Y1315
Lab supporting staffs: YK Au / Kan Chan/Arnold
Demonstrators: Dr. Samuel Lee, Alston Lee, Fu Wai Chung, Guo Shuai, Yuen
On Ying,
Sep 16 Tue
Acetylation of α-D-glucopyranose (Expt 1)
Sep 23 Tue
Cis-1,2,3,6-tetrahydro-4,5-dimethylphthalic anhydride
(Diels-alder reaction) (Expt 2)
Sep 30 Tue
Photochemical Reaction and Acid-catalyzed
Rearrangement: Cycloaddition reactions (Expt.3, Part A) and Michael Addition (Expt 4, part A)
Oct 7 Tue
Michael Addition (Expt 4, part B)
Oct 14 Tue
Photochemical Reaction and Acid-catalyzed
Rearrangement: Cycloaddition reactions (Expt.3, Part B)
Oct 21 Tue
Purification of products and obtain spectrum for samples
Organic Chemistry II Laboratory (ABCT357, ABCT3757) (Group two)
Contact: Alston Lee (alston.lee@polyu.edu.hk)
Wednesday 8:30-11:30 , Laboratory: Y1315
Lab supporting staffs: YK Au / Kan Chan/Arnold
Demonstrators: Alston Lee, Lo Wai Sum, Guo Shuai, Yip Yuk Wang
Sep 17 Wed
Acetylation of α-D-glucopyranose (Expt 1)
Sep 24 Wed
Cis-1,2,3,6-tetrahydro-4,5-dimethylphthalic anhydride
(Diels-alder reaction) (Expt 2)
Oct 8 Wed
Photochemical Reaction and Acid-catalyzed
Rearrangement: Cycloaddition reactions (Expt.3, Part A) and Michael Addition (Expt 4, part A)
Oct 15 Wed
Michael Addition (Expt 4, part B)
Oct 22 Wed
Photochemical Reaction and Acid-catalyzed
Rearrangement: Cycloaddition reactions (Expt.3, Part B)
Oct 29 Wed
Purification of products and obtain spectrum for samples
Page 1 of 8
Expt.1. Acetylation of α-D-glucopyranose
Procedure:
1. Preheat solution of ZnCl2 in a 50mL pear shape flask with air condenser (0.5 g anhydrous ZnCl2 in 12.5 ml acetic anhydride, this will be provided by lab.
(ABCT357/ABCT3757)
Lab Manual
2014-2015
Lee Hang Wai, Alston
(alston.lee@polyu.edu.hk)
Dr. Lee Cheng Hao, Samuel
(chenghao.lee@polyu.edu.hk)
Organic Chemistry II Laboratory (ABCT357, ABCT3757) (Group one)
Contact: Alston Lee (alston.lee@polyu.edu.hk)
Tuesday 8:30-11:30 , Laboratory: Y1315
Lab supporting staffs: YK Au / Kan Chan/Arnold
Demonstrators: Dr. Samuel Lee, Alston Lee, Fu Wai Chung, Guo Shuai, Yuen
On Ying,
Sep 16 Tue
Acetylation of α-D-glucopyranose (Expt 1)
Sep 23 Tue
Cis-1,2,3,6-tetrahydro-4,5-dimethylphthalic anhydride
(Diels-alder reaction) (Expt 2)
Sep 30 Tue
Photochemical Reaction and Acid-catalyzed
Rearrangement: Cycloaddition reactions (Expt.3, Part A) and Michael Addition (Expt 4, part A)
Oct 7 Tue
Michael Addition (Expt 4, part B)
Oct 14 Tue
Photochemical Reaction and Acid-catalyzed
Rearrangement: Cycloaddition reactions (Expt.3, Part B)
Oct 21 Tue
Purification of products and obtain spectrum for samples
Organic Chemistry II Laboratory (ABCT357, ABCT3757) (Group two)
Contact: Alston Lee (alston.lee@polyu.edu.hk)
Wednesday 8:30-11:30 , Laboratory: Y1315
Lab supporting staffs: YK Au / Kan Chan/Arnold
Demonstrators: Alston Lee, Lo Wai Sum, Guo Shuai, Yip Yuk Wang
Sep 17 Wed
Acetylation of α-D-glucopyranose (Expt 1)
Sep 24 Wed
Cis-1,2,3,6-tetrahydro-4,5-dimethylphthalic anhydride
(Diels-alder reaction) (Expt 2)
Oct 8 Wed
Photochemical Reaction and Acid-catalyzed
Rearrangement: Cycloaddition reactions (Expt.3, Part A) and Michael Addition (Expt 4, part A)
Oct 15 Wed
Michael Addition (Expt 4, part B)
Oct 22 Wed
Photochemical Reaction and Acid-catalyzed
Rearrangement: Cycloaddition reactions (Expt.3, Part B)
Oct 29 Wed
Purification of products and obtain spectrum for samples
Page 1 of 8
Expt.1. Acetylation of α-D-glucopyranose
Procedure:
1. Preheat solution of ZnCl2 in a 50mL pear shape flask with air condenser (0.5 g anhydrous ZnCl2 in 12.5 ml acetic anhydride, this will be provided by lab.