My Sisters Keeper

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With the fine instincts of an investigative reporter and intuitive storyteller, Jodi Picoult, already critically acclaimed for her previous best selling novels, zeroes in on the issue of genetically engineered children who are born to save their siblings lives. In the process, she creates a moving saga of a family faced with the inevitable loss of one of their own.

My Sister’s Keeper is a poignant, uplifting, emotional, sad, triumphant, passionate, heartwrenching and extremely powerful story about the Fitzgeralds, a family united in their love for each other but divided on exactly where the boundaries of family obligations, love and sacrifice should end. But it is, ultimately, a story of two sisters, the unbreakable bond they share and how totally entwined they have been all their lives until a crucial decision threatens to tear them apart and ends up changing all the lives forever. The Fitzgeralds - Brian, a firefighter and avid amateur astronomer, and Sara, a stay-at-home mother and ex-lawyer - have the perfect suburban family, but life changes irreversibly when Kate, now sixteen, is diagnosed at age two with leukemia. She develops what looks like "a line of small blue jewels" down her spine, and her mother knows immediately that she is not seeing normal bruises. The family doctor wants the tests repeated in the hospital hematology/oncology department. There, after a series of painful and invasive procedures, they learn that Kate suffers from "APL … a subgroup of myeloid leukemia. The rate of survival … is twenty to thirty percent, if treatment starts immediately." The treatments keep the disease at bay for about five years, until Kate's body explodes with runaway cancer cells. She desperately needs a bone marrow transplant or she will die. Her determined mother, on the advice of the doctor, persuades her husband to try for the "perfectly engineered baby."

Their other child, Jesse, is not a match, but now at thirteen, Anna has always been aware that she...
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