Lab Ducument

Topics: Analytical chemistry, Detection limit, Calibration Pages: 26 (5240 words) Published: March 21, 2013

Quality Assurance Office
San Francisco, California
R9QA/004.2 AUGUST 2001


1.0 2.0 Introduction
General Documentation Requirements
2.1 Data Package Format
2.2 Case Narrative
2.3 Chain-of-Custody
1 2 2 2 3


Organic Analyses Documentation Requirements
4 3.1 Summary of Environmental Sample Results
4 3.2 Summary of QA/QC Sample Results
4 3.2.1 Instrument Calibration
4 3.2.2 Method Blank Analysis
5 3.2.3 Surrogate Standard Recovery
5 3.2.4 Internal Standard Summary
6 3.2.5 Compound Confirmation
6 3.2.6 Peak Resolution Summary
6 3.2.7 Precision and Accuracy
6 3.2.8 Other QC Criteria
7 3.3 Raw Data 7 Gas Chromatographic Analyses
3.3.1 8 Gas Chromatographic/Mass Spectrometric
3.3.2 8 Analyses
3.3.3 High Performance Liquid 9 Chromatographic Analyses 3.3.4 10 Immunoassay Analyses Inorganic Analyses Documentation Requirements 4.1 Summary of Environmental Sample Results
4.2 Summary of QA/QC Sample Results
4.2.1 Instrument Calibration Verification
4.2.2 Blank Analysis

Inductively Coupled Plasma Atomic
Emission / Mass Spectrometry
Interference Check Samples
Precision and Accuracy
Other QC Criteria
4.3 Raw Data
Inductively Coupled Plasma Atomic
Emission Spectrometric Analyses
Inductively Coupled Plasma Mass
Spectrometric Analyses
Atomic Absorption and Atomic Emission
Ion Chromatographic Analyses
Titrimetric and Colorimetric
Gravimetric Analyses
12 12 12 12 13 13 14 14 15 15 16 17 18 18 19


Appendices Appendix A

Appendix B

Suggested Summary Forms for Common Organic Methods
Suggested Summary Forms for Common Inorganic Methods References

A - 1
A - 2
B - 1

1.0 INTRODUCTION In order for data to be used for decision-making purposes it is essential that it be of known and documented quality. Verification and validation of data requires that appropriate quality assurance and quality control (QA/QC) procedures be followed, and that adequate documentation be included for all data generated both in the laboratory and in the field. The QA/QC documentation provided by any laboratory, in conjunction with sample results, allows for evaluation of the following indicators of data quality: C C C C C C

Integrity and stability of samples;
Instrument performance during sample analysis;
Possibility of sample contamination;
Identification and quantitation of analytes;
Analytical precision; and
Analytical accuracy.

General laboratory documentation requirements discussed in this document are formatted into two sections, organic and inorganic analyses. These specifications are intended to establish general, analytical documentation requirements that contract and subcontract laboratories should meet when generating data for USEPA Region IX. However, project or contract requirements may supercede this document. In order to fulfill project specific objectives, laboratories may be required to supply additional documentation. Users should defer to project specific planning documents to determine if they are required to provide any additional information in deliverables. Questions or comments concerning this document should be directed to Carl Brickner, Jr., USEPA Region IX Quality Assurance Office, at (415) 744-1536 or



The data package submitted to EPA should consist of five sections: C C C C C

Case narrative;
Chain-of-Custody (COC) documentation;
Summary of results for environmental samples;
Summary of QA/QC results; and
Raw data.

Summaries of data and results may be presented in a Contract Laboratory Program (CLP) type format or any equivalent that supplies the required information as stated below. All laboratory data qualifiers shall be...
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