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World Review of Science, Technology and Sustainable Development, Vol. 4, Nos. 2/3, 2007

Nanotechnology in cancer prevention, detection and treatment: bright future lies ahead G. Ali Mansoori Departments of Bio and Chemical Engineering, University of Illinois at Chicago, 218 SEO, 851 S, Morgan St. (M/C 063), Chicago, IL 60607-7052, USA E-mail: mansoori@uic.edu

Pirooz Mohazzabi*
Department of Physics, University of Wisconsin – Parkside, Kenosha, WI 53141, USA E-mail: pirooz.mohazzabi@uwp.edu *Corresponding author

Percival McCormack
Department of BioEngineering, University of Illinois at Chicago, 218 SEO, 851 S. Morgan St. (M/C 063), Chicago, IL 60607-7052, USA E-mail: pmccorm@uic.edu

Siavash Jabbari
Department of Radiation Oncology, University of California – San Francisco 1600 Divisadero Sreet, Suite H1031, San Francisco, CA 94143-1708, USA E-mail: siavashjabbari@gmail.com Abstract: This paper is an overview of advances and prospects in applications of nanotechnology for cancer prevention, detection and treatment. We begin with a brief description of the underlying causes of cancer. Then we address preventive treatment, disease-time treatment, and diagnosis in the context of some of the most recent advances in nanotechnology. Nanoparticle science is also briefly addressed as the foundation upon which most nanotechnology cancer therapy is based. It is demonstrated how nanotechnology can help solve one of the most challenging and longstanding problems in medicine, which is how to eliminate cancer without harming normal body tissue.

Copyright © 2007 Inderscience Enterprises Ltd.

Nanotechnology in cancer prevention, detection and treatment Keywords: cancer; diamondoid; folate receptor; hyperthermia method; nanoparticle; melanoma; nanocrystal; nanobiotechnology; nanotechnology; quantum dot. Reference to this paper should be made as follows: Ali Mansoori, G., Mohazzabi, P., McCormack, P. and Jabbari, S. (2007) ‘Nanotechnology in cancer prevention, detection and treatment: bright future lies ahead’, World Review of Science, Technology and Sustainable Development, Vol. 4, Nos. 2/3, pp.226–257. Biographical notes: G. Ali Mansoori is a Professor of Bio and Chemical Engineering. He received his undergraduate education at Tehran University, his graduate education at the Universities of Minnesota and Oklahoma, all in chemical engineering, and he was a postdoctoral fellow at Rice University. He has published extensively in the areas of nanotechnology, biotechnology, energy technology, thermodynamics and statistical mechanics. He is a Consultant and Lecturer to numerous bio, chemical, energy and health-related industries and research centres. For his research achievements he has received numerous recognitions including the UNESCO medal of fundamental science, Algorithm scientific international award and the Russian Academy of Natural Sciences Kapitsa gold medal. Pirooz Mohazzabi is a Professor of Physics at the University of Wisconsin-Parkside. He received his undergraduate degree in Chemistry from Tehran University in 1969, his MSc and PhD Degrees in Materials Science and Engineering from the University of California, Berkeley in 1972 and 1975, respectively. He has over 30 years of research and teaching experience in physics, materials science and chemistry. He has published extensively in the areas of condensed matter physics, materials science, thermodynamics and statistical mechanics, nanotechnology, applied mathematics, classical and quantum mechanics, as well as pedagogical aspects of physics. Percival McCormack is an Adjunct Professor of Bioengineering, Biophysics and Physiology. He has BA (Physics and Mathematics), MSc (Computer Science), PhD (Nuclear Physics), ScD (published work) and MD (medicine) all from Trinity College, Dublin. He received many fellowships and honours including senior medical research fellow (National Cancer Institute), fellow (Institute of Physics, London), fellow (Royal Society...
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