Santa Barbara College
8 December 2011
The following paper will show descriptions and possible causes of the condition of Hodgkin’s disease. In addition, this paper will highlight signs and symptoms, possible complications that could occur, tests to be taken, possible treatment options, activity, diet restrictions, and finally, the possible outcome for patients with Hodgkin’s disease
Hodgkin's disease is a cancer of the lymphatic system, which is part of your immune system. In Hodgkin's disease, cells in the lymphatic system grow abnormally and may spread beyond the lymphatic system. The lymphatic system helps the body's immune system to filter out bacteria, viruses, and other unwanted substances (Lowry, L., 2010). The lymphatic system includes the lymph nodes which are sometimes called glands, thymus, spleen, tonsils, adenoids, and bone marrow, as well as the channels called lymphatic’s or lymph vessels that connect them (Lowry, L., 2010)
Lymphoma is a disease in which cancer cells form in a person's lymphatic system and start to grow uncontrollably. There are several different types of lymphomas, and they are divided into two broad categories: Hodgkin's disease and non-Hodgkin's lymphoma. Lymphomas that involve a particular type of cell, called a Reed-Sternberg cell, are classified under the heading Hodgkin's disease (Wagner, H., 2004). There are several different subtypes of Hodgkin's disease, based on how the cancerous tissue looks under a microscope. Lymphomas that do not contain Reed-Sternberg cells are classified under the heading non-Hodgkin's lymphomas.
It's not clear what causes Hodgkin's lymphoma. People who have a brother or sister who has had Hodgkin's disease seem to be slightly more likely to get the disease, as are people who have had an organ transplant or who have acquired immunodeficiency syndrome AIDS (Wagner, H., 2004).
Doctors know that most Hodgkin's lymphoma occurs when an infection-fighting cell called a B cell develops a mutation in its DNA(Wagner, H., 2004). The mutation tells the cells to divide rapidly and to continue living when a healthy cell would die. The mutation causes a large number of oversized, abnormal B cells to accumulate in the lymphatic system, where they crowd out healthy cells and cause the signs and symptoms of Hodgkin's disease (Wagner, H., 2004). Classical Hodgkin's lymphoma is the more common type of this disease. It can be broken down further into subtypes. People diagnosed with classical Hodgkin's lymphoma have large, abnormal cells called Reed-Sternberg cells in their lymph nodes (Wagner, H., 2004)
There are many symptoms associated with Hodgkin’s disease. The first and foremost is painless swelling of the lymph nodes in the neck, armpits, or groin. Hodgkin’s disease makes the patient very fatigued. In addition to fatigue, frequent fever and chills come and go sporadically.
Individuals have been recorded has being itchy all over the body that cannot be explained or pinpointed. Loss of appetite, a patient may lose as much as 10 percent or more of his or her body weight. Other symptoms associated with Hodgkin’s disease include coughing, chest pains, or breathing problems if there are swollen lymph nodes in the chest, excessive sweating, pain or feeling of fullness below the ribs due to swollen spleen or liver, pain in lymph nodes after drinking alcohol and last skin blushing or flushing.
It is very important to consult a doctor when one is feeling irregular. If you believe you may...