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Antiemetics are therapeutic agents which are used to treat vomiting and nausea caused by several medical conditions. Nausea and vomiting are not diseases, they are symptoms associated with a variety of medical conditions such as gastroenteritis, motion sickness, dizziness, pregnancy, overeating, emotional stress and food poisoning. Nausea is a condition of unease in the stomach with an involuntary desire to vomit, this often occurs before vomiting. Various antiemetics used to treat vomiting and nausea are dolasetron, olanzapine, alizapride, cyclizine, promethazine and lorazepam. Some of the commercially available brands of antiemetics are Phenergan (promethazine) by Baxter Healthcare Corporation and Zyprexa (olanzapine) by Eli Lilly.
The market for antiemetics is segmented on the basis of different class of drugs used to treat emesis and nausea such as 5-HT3 receptor antagonists, dopamine antagonists, NK1 receptor antagonists, anticholinergics and others. 5HT3 receptor antagonists act by blocking serotonin receptors in the central nervous system and gastrointestinal tract and comprises of dolastron, ondansetron and tropistron. Dopamine antagonists include domperidone, olanzapine and alizapride while aprepitant and casopitant are NK1 receptor antagonists.
The market for antiemetic drugs is projected to grow worldwide under the influence of increasing incidences of cancer, increased number of surgical procedures being conducted worldwide and other diseases. As mentioned earlier nausea and vomiting are not diseases but they are symptoms and side effects of a variety of diseases including cancer, gastroenteritis, surgeries and early stages of pregnancy. The market of antiemetic drugs will experience along with the increasing incidences of the aforementioned...