Genetics and Molecular Biology

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Faculty of Science

Undergraduate Modular Scheme

Session 2010/2011

Semester 2

Level 4

MODULE:LS1180: Genetics and Molecular Biology

DATE:31 May 2011

TIME:09.30 – 11.30

Instructions to Candidates

This paper contains THIRTY-EIGHT questions in FIVE sections: Sections A, B, C, D and E. Answer THIRTY-FOUR questions only
Section A:THIS SECTION HAS BEEN WITHHELD BY THE FACULTY
Answer ALL THIRTY questions on the MCQ sheet provided
Section B:Answer ONE question
Section C:Answer ONE question
Section D:Answer ONE question
Section E:Answer ONE question

Section A is worth 30 marks and Sections B to E are worth 15 marks each

ANSWER SECTIONS B TO E IN SEPARATE ANSWER BOOKS

CANDIDATES ARE PERMITTED TO BRING ONE APPROVED CALCULATOR INTO THIS EXAMINATION: from either Casio FX83 or Casio FX85 series (with any suffix), FX115MS, FX570ES or FX991ES

Invigilators are under instruction to remove any other calculators

Number of Pages: 1 – 9

SECTION A

Each question has only ONE correct answer

THIS SECTION HAS BEEN WITHHELD BY THE FACULTY

Continued..
SECTION B

Answer ONE question from this section

1. Draw an annotated diagram to illustrate the initiation of transcription in Eukaryotes. Label components in the diagram, as necessary, and briefly outline the process. (15 marks)

2. Name five factors that influence the distribution of genes in a population to upset the Hardy Weinberg equilibrium, and describe each using an example (15 marks)

SECTION C

Answer ONE question from this section

3. The following is a pedigree of a family in which a rare form of colour blindness is found (filled-in symbols). Indicate as much as you can about the genotypes of all individuals in the pedigree.

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(15 marks)

4. A locus that affects susceptibility to a degenerative brain disease has two alleles, A and a. In a population, 16 people have...
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