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Gender Differences in Depression

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Gender Differences in Depression
CURRENT DIRECTIONS IN PSYCHOLOGICAL SCIENCE

173

Gender Differences in Depression
Susan Nolen-Hoeksema1
Department of Psychology, University of Michigan, Ann Arbor, Michigan

Abstract From early adolescence through adulthood, women are twice as likely as men to experience depression. Many different explanations for this gender difference in depression have been offered, but none seems to fully explain it. Recent research has focused on gender differences in stress responses, and in exposure to certain stressors. I review this research and describe how gender differences in stress experiences and stress reactivity may interact to create women’s greater vulnerability to depression. Keywords gender; depression; stress

Across many nations, cultures, and ethnicities, women are about twice as likely as men to develop depression (Nolen-Hoeksema, 1990; Weissman et al., 1996). This is true whether depression is indexed as a diagnosed mental disorder or as subclinical symptoms. Diagnosable depressive disorders are extraordinarily common in women, who have a lifetime prevalence for major depressive disorder of 21.3%, compared with 12.7% in men (Kessler, McGonagle, Swartz, Blazer, & Nelson, 1993). Most explanations for the gender difference in depression have focused on individual variables, and studies have attempted to show that one variable is better than another in explaining the difference. In three decades of research, however, no one variable

has single-handedly accounted for the gender difference in depression. In recent years, investigators have moved toward more integrated models, taking a transactional, developmental approach. Transactional models are appropriate because it is clear that depression impairs social and occupational functioning, and thus can have a major impact on an individual’s environment. Developmental models are appropriate because age groups differ markedly in the gender difference in depression. Girls are no more likely than boys



References: Breslau, N., Davis, G.C., Andreski, P., Peterson, E.L., & Schultz, L. (1997). Sex differences in posttraumatic stress disorder. Archives of General Psychiatry, 54, 1044–1048. Cutler, S., & Nolen-Hoeksema, S. (1991). Accounting for sex differences in depression through female victimization: Childhood sexual abuse. Sex Roles, 24, 425–438. Cyranowski, J.M., Frank, E., Young, E., & Shear, K. (2000). Adolescent onset of the gender difference in lifetime rates of major depression. Archives of General Psychiatry, 57, 21–27. Kessler, R.C., McGonagle, K.A., Swartz, M., Blazer, D.G., & Nelson, C.B. (1993). Sex and depression in the National Comorbidity Survey I: Lifetime prevalence, chronicity, and recurrence. Journal of Affective Disorders, 29, 85–96. Nolen-Hoeksema, S. (1990). Sex differences in depression. Stanford, CA: Stanford University Press. Nolen-Hoeksema, S. (1995). Gender differences in coping with depression across the lifespan. Depression, 3, 81–90. Nolen-Hoeksema, S., & Girgus, J.S. (1994). The emergence of gender differences in depression in adolescence. Psychological Bulletin, 115, 424–443. Nolen-Hoeksema, S., Larson, J., & Grayson, C. (1999). Explaining the gender difference in depression. Journal of Personality and Social Psychology, 77, 1061–1072. Weiss, E.L., Longhurst, J.G., & Mazure, C.M. (1999). Childhood sexual abuse as a risk factor for depression in women: Psychosocial and neurobiological correlates. American Journal of Psychiatry, 156, 816–828. Weissman, M.M., Bland, R.C., Canino, G.J., Faravelli, C., Greenwald, S., Hwu, H.-G., Joyce, P.R., Karam, E.G., Lee, C.-K., Lellouch, J., Lepine, J.P., Newman, S.C., Rubio-Stipc, M., Wells, E., Wickramaratne, P.J., Wittchen, H.-U., & Yeh, E.K. (1996). Cross-national epidemiology of major depression and bipolar disorder. Journal of the American Medical Association, 276, 293–299. Young, E., & Korszun, A. (1999). Women, stress, and depression: Sex differences in hypothalamic-pituitary-adrenal axis regulation. In E. Leibenluft (Ed.), Gender differences in mood and anxiety disorders: From bench to bedside (pp. 31–52). Washington, DC: American Psychiatric Press. Zahn-Waxler, C. (2000). The development of empathy, guilt, and internalization of distress: Implications for gender differences in internalizing and externalizing problems. In R. Davidson (Ed.), Wisconsin Symposium on Emotion: Vol. 1. Anxiety, depression, and emotion (pp. 222–265). Oxford, England: Oxford University Press. Note 1. Address correspondence to Susan Nolen-Hoeksema, Department of Psychology, University of Michigan, 525 E. University Ave., Ann Arbor, MI 48109; e-mail: nolen@umich.edu. Published by Blackwell Publishers Inc.

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