– Endocrine System

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Week 3 Lab 4 – Endocrine System Physiology - Activities 1-4 pages 43 - 48

Latasha Roberts
March 25, 20012
SC145L-8H
Introduction:
(please post an introduction to the lab, include what you will be doing for each activity)

Activity 1: Determining Baseline Metabolic Rates

Data: (add your results here in numbers - Chart 1 is used in Activities 1-4)

Chart 1 – Effects of Hormones on Metabolic Rate
Rat Types
Baseline:NormalThyroidectomizedHypophysectomized
Weight249.9g245.3g244.4g
ml O2, 1 min.7.0ml6.1ml6.1ml
ml O2/hr.420ml366ml366ml
Metabolic Rate1680.72ml O2/kg/hr 1492.45ml/O2/kg/hr 1497.54ml/O2/kg/hr

With thyroxine:
Weight250.0g245.1g244.9g
ml O2, 1 min.7.9ml7.5ml7.4ml
ml O2/hr.474ml450ml444ml
Metabolic Rate1896ml O2/kg/hr 1835.98 ml O2/kg/hr1812.98ml O2/kg/hr

With TSH:
Weight250.0g245.3g245.8g
ml O2, 1 min.7.9ml6.1ml7.5ml
ml O2/hr.474ml366ml450ml
Metabolic Rate1896ml O2/kg/hr 1492.45ml/O2/kg/hr1830.75 ml/O2/kg/hr

With propylthiouracil:
Weight250.0g245.3g244.4_g
ml O2, 1 min.6.1ml6.1ml6.1ml
ml O2/hr.366_ml366ml366ml
Metabolic Rate1464ml O2/kg/hr 1492.45 ml O2/kg/hr1497.54 ml O2/kg/hr

Questions: answer each question; use full sentences; ask instructor if you need help 1-1: Which rat had the fastest baseline metabolic rate? Normal Rat

1-2: Why did the metabolic rates differ? The hypophysectomized rat lacked thyroid-stimulating hormone. The thyroidectomized rat lacked thyroxine hormone.

Summary:

In this Activity, I learned/observed that: write 1-2 sentences on what you observed by doing this experiment – think “big picture”

Activity 2: Determining the Effect of Thyroxine on Metabolic Rate

Data:
Fill in Chart 1

Questions: answer each question; use full sentences; ask instructor if you need help 2-1: What was the effect of thyroxine on the normal rat's...
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