Drug Stdy

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  • Topic: Gastric acid, Stomach, Chemotherapy
  • Pages : 8 (2297 words )
  • Download(s) : 130
  • Published : October 3, 2012
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DRUG NAME| ACTION| INDICATION| CONTRAINDICATION| ADVERSE REACTION| NURSINGRESPONSIBILITIES| GENERIC:Piperacilin + TazobactamBRAND NAME:PiptazoDOSAGE:4.5gFREQUENCYQ8ROUTE:IV| CLASSIFICATION:Antibiotic;Piperacillin and enzyme inhibitor. Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections| intra – abdominal linfections w/ peritonitis| Hypersensitivity to penicillins, cephalosporins & β-lactam inhibitors|  Hypersensitivity Reactions: Rash, pruritus and fever have been reportedGastrointestinal Effects: melena, gastritisHepatic Effects: Transient increases in aspartate aminotransferase (AST),alanine aminotransferase(ALT), alkaline phosphatase and bilirubin can occur.Renal Effects: Increases in serum concentrations of creatinine and blood urea nitrogen (BUN) may be observed.Effect on the Central Nervous System: Headache, MalaiseLocal Reactions: pain, inflammation, thrombophlebitis and edema| Piptaz should not be added to blood products or albumin hydrolysates and should not be mixed with other drugs in a syringe or infusion bottle due to possible problems with compatibility.Piptaz is not chemically stable in solutions that contain only sodium bicarbonate and solutions that significantly alter pH.Lactated Ringer's Solutionis not compatible with Piptaz.Piptaz is stable in glass and plastic containers (plastic syringes, IV bags and tubing) once used with compatible diluents| DRUG NAME| ACTION| INDICATION| CONTRAINDICATION| ADVERSE REACTION| NURSINGRESPONSIBILITIES| GENERIC:AcetylcysteineBRAND NAME:FluimucilDOSAGE:1 sachet in 100 ml of waterFREQUENCYTIDROUTE:oral| Exerts mucolytic action through its free sulfhydryl group which opensup the disulfide bonds in the mucoproteins thus lowering mucous viscosity. The exact mechanism of action in acetaminophen toxicity is unknown. It is thought to act by providing substrate for conjugation with the toxic metabolite..CLASSIFICATION:Mucolytic Agent| Treatment of respiratory affections characterized by thick and viscous hypersecretions | - Hypersensitivity-MAO inhibitor therapy within 14 days initiating therapy; severe hypertension; severe. Coronary artery disease, hypersensitivity to pseudoedephrine,acrivastine or any component; renal impairment| * Hypersensitivity reactions have been reported in patients receiving acetylcysteine, including bronchospasm, angioedema, rashes and pruritus, may occur. Other adverse effects reported include nausea and vomiting, fever, syncope, sweating, arthralgia, blurred vision, disturbances of liver function| Monitor effectiveness of therapy and advent of adverse/allergic effects. Instruct patient in appropriate use and adverse effects to report| DRUG NAME| ACTION| INDICATION| CONTRAINDICATION| ADVERSE REACTION| NURSINGRESPONSIBILITIES| GENERIC:OmeprazoleBRAND NAMELosec (CAN)DOSAGE:40 mgFREQUENCYODROUTE:IV| Gastric acid-pump inhibitor: Suppresses gastric acid secretion by specific inhibition of the hydrogen-potassium ATPase enzyme system at the secretory surface of the gastric parietal cells; blocks thefinal step of acid production.CLASSIFICATION:Antisecretory drugProton Pump inhibitor| short-term treatment of activeduodenal ulcer;First-line therapy intreatment of heartburn orsymptoms of gastroesophageal refluxdisease (GERD)| Contraindicated with hypersensitivity to omeprazole or its components;Use cautiously with pregnancy,lactation.|  CNS: Headache, dizziness ,asthenia, vertigo, insomnia ,apathy, anxiety, parenthesis, dream abnormalitiesDermatologic : Rash, inflammation, urticaria, pruritus, alopecia, dry skinGI: Diarrhea, abdominal pain, nausea, vomiting, constipation, dry mouth, tongue atrophyRespiratory : URI symptoms,cough, epistaxisOther: fever| Always be alert that it is an Antisecretory drug;Proton pump inhibitor...
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