Details of Antihistamine Drugs

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a. The names given are the Generic name, you need to find the Brand name and the company that produces it. Loradatine : Claritin, Schering-Plough

b. What is the mechanism of action.
Like other H1-blockers, loratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Claritin also has a weak affinity for acetylcholine and alpha-adrenergic receptors.

c. What is the use of the medication. The specific conditions that are treated with it. Claritin is an antihistamine that relieves the sneezing, runny nose, stuffiness, itching, and tearing eyes caused by hay fever or other upper respiratory allergies. It also relieves the swollen, red, itchy patches of skin caused by hives. Claritin is also available as an over-the-counter product.

d. Side Effect of the prescription drug.
Common side effects include:
dry mouth
This medicine can cause excitement especially in children.
See a doctor immediately if you experience:
fast or irregular heartbeat
mental or mood changes
tightness in the chest
unusual tiredness or weakness.

e. Any important fact that calls your attention.
If you have liver or kidney disease, your doctor should prescribe a lower starting dose of Claritin.

f. Dosage and how should it be taken.
10 mg tablets per day, to be administered orally

g. When should not be prescribed.
Do not take Claritin if you are sensitive to or have ever had an allergic reaction to it. Make sure your doctor is aware of any drug reactions that you have experienced.

h. Possible food and prescription drug Interaction.
Although no harmful interactions with Claritin have been reported, there is a theoretical possibility of an interaction with the following drugs:
Antibiotics such as erythromycin
Cimetidine (Tagamet)
Ketoconazole (Nizoral)
Do NOT take this medicine with...
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