Cipro

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Drug classification: Cipro

Major Drug Classification:
Antiinfectives/ broad spectrum

Major Drug Actions for this classification:
Interferes with conversion of intermediate DNA fragments into high-molecular weight DNA in bacteria; DNA gyrase inhibitor

Uses for drugs in this classification:
Adult urinary tract infections (including complicated); chronic bacterial prostatitis; acute sinusitis; infectious diarrhea; typhoid fever; complicated intraabdominal infections; nosocomial pneumonia; exposure to inhalation anthrax

Common Adverse reactions and Side Effects from drugs in this classification: CNS: Headache, dizziness, fatigue, insomnia, depression, restlessness, seizures, confusion. GI: Nausea, increased ALT, AST, flatulence, heartburn, vomiting, diarrhea, oral candidiasis, dysphagia, pseudomembranous colitis, dry mouth. HEMA: Bone marrow depression INTEG: Rash, pruritus, urticarial, photosensitivity, flushing, fever, chills, toxic epidermal necrolysis. MISC: Anaphylaxis, Stevens-Johnson syndrome, visual impairment, QT. prolongations. MS: Tremor, arthralgia, tendon rupture

Nursing Implications:
Assessments required before administration (include nursing assessment, labs, etc.) Assess pt for previous sensitivity reaction. Assess pt for signs and symptoms of infection including characteristics of wounds sputum, urine, stool, WBC >10,000/mm3, fever; obtain baseline information before, during treatment. Obtain C&S before beginning product therapy to identify if correct treatment has been initiated. Assess for anaphylaxis: rash, urticarial, dyspnea, pruritus, chills, fever, joint pain; may occur a few days after therapy begins; epinephrine and resuscitation equipment should be available for anaphylactic reaction. Identify urine output; if decreasing, notify prescriber (may indicate nephrotoxicity); also check for increased BUN, creatinine. Monitor blood studies: AST. ALT. CBC. Hct, bilirubin, LDH, alkaline phosphatase, Coombs’ test monthly if...
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