Chapter 13 Review

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  • Topic: DNA, Gene expression, Gene
  • Pages : 35 (9122 words )
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  • Published : December 8, 2012
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When lactose becomes available the genes encoding β-galactosidase and lactose permease are upregulated in E. coli.

true

2
Different globin polypeptides are expressed at similar levels during the embryonic and fetal stages of mammalian development.

false

3
RNA polymerase can bind to the promoter region of the DNA even when the lac repressor is bound to the operator site.

true
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4
Both eukaryotes and prokaryotes require a promoter region for gene transcription.

true

5
Eukaryotic genes are almost always organized in groups, similar to operons in prokaryotes.

false

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6
Unmethylated CpG islands are correlated with inactive genes.

false

7
Loosely packed chromatin is said to be in an open conformation.

true

8
MicroRNAs increase the rate of mRNA translation.

false

9
The ability of cells to control their level of gene expression is called

gene regulation

10
Some genes such as that for β-actin are expressed at relatively constant levels in tissues regardless of variations in the animal's condition. What do we call this type of gene?

constitutive gene

11
Liver cells, mammary cells, and skin cells all contain the same genome; however, their respective proteomes vary drastically. This observation is best explained by what phenomenon?

cell differentiation

12
Which of the following are points of control for gene expression in eukaryotes?

all choices correct

13
What type of regulatory transcription factor binds DNA and increases the transcription of a gene?

an activator exerting positive control

14
Why is the operon arrangement of genes beneficial to certain bacteria?

it allows the coordinated regulation of a group of genes that encode proteins with a common function.

15
An mRNA that contains the coding sequence for two or more structural genes is called a

c. polycistronic mRNA.

16
Which of the following would occur if there were a mutation in the lacO site (lac Operator) of the lac operon?

Binding of a repressor protein could be hindered.

17
Which of the following occurs when allolactose levels increase in E. coli?

Transcription of genes within the lac operon increases.

18
The ability of glucose to repress the lac operon depends on which of the following effector molecules?

cAMP

19
Which of the following occurs when the cAMP-CAP complex binds the CAP site near the lac promoter?

e. RNA polymerase binds to the promoter and transcription rate increases.

20
A(n) ________ operon is one whose transcription is repressed by effector molecules.

repressible

21
Which of the following is a FALSE statement about the difference in gene regulation between prokaryotes and eukaryotes?

d. Eukaryotic genes are arranged into operons, while prokaryotic genes are not.

22
What is the effect of DNA methylation?

inhibits transcription

23
Which of the following protein(s) does NOT play a role in initiating transcription in eukaryotes?

b. transposase

24
An activator is to an enhancer as a(n) _____ is to a silencer.

repressor

25
Which of the following does NOT occur during transcriptional regulation in eukaryotes?

Chromatin is converted to the closed conformation.

26
Which of the following is a characteristic of microRNAs (miRNAs)?

all choices are correct

27
When cytosolic levels of iron increase, intracellular ferritin levels will

increase

28
Eukaryotic DNA methylation occurs on which base?

cytosine

29
Which of the following is NOT true of the gucocorticoid receptor?

b. When bound to glucocorticoids, the receptors will bind covalently...
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