American Cancer Society
The Leukemia and Lymphoma Society
The Children’s Oncology Group
Professor Elisa Ratliff
Genetic Disorder Brochure Project
Natalie Marie Walker
Diagnosed with Burkitt’s lymphoma on June 24th, 2011
Natalie turned 2 on
June 29th, 2011
What is non-Hodgkin Lymphoma?
A cancer that develops from cells that makes up the lymph system. The lymph system includes specialized cells and organs, such as the lymph nodes, spleen, tonsils, and bone marrow. They are responsible for helping to protect the body from infection. Non-Hodgkin lymphoma can start anywhere in the body, however, is most often located in the head/neck area, chest and abdomen. What type of non-Hodgkin Lymphoma occurs in Children?
Three main types occur in children:
1) Small B-cell, known as Burkitt’s lymphoma. Occurs in 30-40% of cases, usually found in abdomen. 2) Lymphoblastic lymphoma. Occurs approximately in 30% of cases, usually found in the chest. 3) Large cell lymphoma. Occurs in 30-35% of cases, can be found in the lungs, bones, skin and various lymph nodes. Burkitt’s Lymphoma
A non-Hodgkin Lymphoma
Symptoms, Causes and testing
for Burkitt’s Lymphoma
Burkitt’s lymphoma Causes:
* Some association with the Epstein-Barr virus, mononucleosis, HIV and AIDS * An abnormality of chromosome #8 is present
* Not inherited, however, children with an inherited disease have an increased chance to develop non-Hodgkin lymphoma * Ultimately, the cause is unknown
Age of Onset
Non-Hodgkin lymphoma accounts for approximately 4-5% of cancer in children with about 800 cancer cases diagnosed each year in the United States. * Rare in children younger than 2
* Occurs most often in children ages 5-14
There is an increased incidence in boys compared to girls, with a ratio of 3:1. Symptoms
Many patients notice large...