Bronchial Asthma
Bronchial asthma (BA) - is a chronic inflammatory disease of the airways in which many cells are involved, and cell components. Chronic inflammation leads to the development of bronchial hyperresponsiveness that leads to recurrent episodes of wheezing, shortness of breath, feeling of fullness in the chest and cough, especially at night or early in the morning. These episodes are usually associated with widespread but variable in their severity of airway obstruction in the lungs, which is often reversible either spontaneously or under the influence of treatment.
Bronchial asthma (BA) is a global health problem; there are about 300 million. asthmatic patients.
In the etiology of asthma play an important role: the genetic characteristics and environment. internal factors genetic: genes predisposing to atopy, genes that predispose to bronchial hyperreactivity.
Obesity (BMI> 30 kg / m2)
Gender (male - in children younger than 14 years)
External factors: allergens: premises allergens: house dust mites, wool do¬mashnih animals (dogs, cats, mice) taraka¬nov allergens, fungi, including mold and yeast, external allergens: pollen, fungi, including yeasts and molds.
Infections (mostly viral).
Professional sensitizers (substances of low molecular weight and high activity - an isocyanate, a platinum salt, a nickel salt, grain dust, flour, etc.).
Tobacco smoke (passive smoking, active smoking).
Air pollution indoors and outdoors.
Food (increased consumption of foods high degree of processing and reduced - antioxidants, increased intake of n-6 polyunsaturated fatty acid (in the composition of margarine and vegetable oils).
Mechanisms of asthma.
Inflammation of the airways - the leading morphological feature of asthma. Inflammatory process covers all respiratory tract, including the upper sections and nasal cavity, especially the bronchi medium caliber. The inflammatory process has a universal character with different clinical forms of asthma.
The special features of inflammation
Bronchial asthma (BA) is a global health problem; there are about 300 million. asthmatic patients.
In the etiology of asthma play an important role: the genetic characteristics and environment. internal factors genetic: genes predisposing to atopy, genes that predispose to bronchial hyperreactivity.
Obesity (BMI> 30 kg / m2)
Gender (male - in children younger than 14 years)
External factors: allergens: premises allergens: house dust mites, wool do¬mashnih animals (dogs, cats, mice) taraka¬nov allergens, fungi, including mold and yeast, external allergens: pollen, fungi, including yeasts and molds.
Infections (mostly viral).
Professional sensitizers (substances of low molecular weight and high activity - an isocyanate, a platinum salt, a nickel salt, grain dust, flour, etc.).
Tobacco smoke (passive smoking, active smoking).
Air pollution indoors and outdoors.
Food (increased consumption of foods high degree of processing and reduced - antioxidants, increased intake of n-6 polyunsaturated fatty acid (in the composition of margarine and vegetable oils).
Mechanisms of asthma.
Inflammation of the airways - the leading morphological feature of asthma. Inflammatory process covers all respiratory tract, including the upper sections and nasal cavity, especially the bronchi medium caliber. The inflammatory process has a universal character with different clinical forms of asthma.
The special features of inflammation