Breast Cancer in Men

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Breast Cancer in Men
Rose Marie Francis
September 27, 2011
Dr. Leroy Isaacs

Breast Cancer in Men
Less than 1% of all breast cancer occurs in men, and although the disease is rare, the incidence appears to be increasing. Because men usually do not suspect breast cancer when they feel a lump in the breast, diagnosis frequently is delayed. Although screening for breast cancer is not recommended for men, radiographic imaging plays an important role in distinguishing benign conditions from malignant disease, and mammography usually is recommended as the first radiographic assessment. Ultrasonography is useful in differentiating between noncancerous cysts and solid malignant tumors, especially if coexisting gynecomastia masks a cancerous lesion on mammography. Sonography also is useful to guide breast biopsy (Anne Mattarella, BS, ELS 2010).

Breast cancer in men is rare, with an incidence of 1% of all breast cancer cases (centers for Disease Control and Prevention). One case of male breast cancer occurs for every 150 cases of female breast cancer (Hill TD, Khamis HJ, 2005), and 0.1% of all male cancers are breast cancers (Breast Cancer Res Treat 2004). Of the 188,467 individuals who were diagnosed with breast cancer in 2005, 1764 were men, and 375 men died from the disease (Cancers for Disease Control and Prevention). In 2009, 1910 new cases of male breast cancer were expected to be diagnosed and 440 men were projected to die from the disease (CA Cancer J Clin 2009). The lifetime risk of developing male breast cancer is about 1 in 1000 (American Cancer Society 2009). The rate of breast cancer in men has been increasing (Hill TD, Giordano SH, Perkins G, et. 2004-2005). Benign Breast conditions

Most breast masses in men are caused by gynecomastia, which is an increase in fibroglandular breast tissue in 1 or both breasts (Egan RL, WB Saunders 1988). Men rarely develop benign breast tumors, such as papillomas, subcutaneous leiomyomas,...
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