Barbiturates: Antibiotic

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  • Topic: Bacteria, Cephalosporin, Penicillin
  • Pages : 8 (1378 words )
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  • Published : August 12, 2012
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Generic name| Brand names| Common uses[2]| Possible side effects[2]| Mechanism of action| Aminoglycosides|
Amikacin| Amikin| Infections caused by Gram-negative bacteria, such asEscherichia coli and Klebsiellaparticularly Pseudomonas aeruginosa. Effective against Aerobic bacteria (not obligate/facultative anaerobes) andtularemia.| * Hearing loss * Vertigo * Kidney damage| Binding to the bacterial 30S ribosomal subunit (some work by binding to the 50S subunit), inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and also causing misreading of mRNA, leaving the bacterium unable to synthesize proteins vital to its growth.| Gentamicin| Garamycin| | | |

Kanamycin| Kantrex| | | |
Neomycin| Mycifradin| | | |
Netilmicin| Netromycin| | | |
Tobramycin| Nebcin| | | |
Paromomycin| Humatin| | | |
Ansamycins|
Geldanamycin| | Experimental, as antitumor antibiotics| | | Herbimycin| | | | |
Carbacephem|
Loracarbef| Lorabid| Discontinued| | prevents bacterial cell division by inhibiting cell wall synthesis.| Carbapenems|
Ertapenem| Invanz| Bactericidal for both Gram-positive and Gram-negative organisms and therefore useful for empiric broad-spectrum antibacterial coverage. (Note MRSA resistance to this class.)| * Gastrointestinal upset and diarrhea * Nausea * Seizures * Headache * Rash and allergic reactions| Inhibition of cell wall synthesis| Doripenem| Doribax| | | |

Imipenem/Cilastatin| Primaxin| | | |
Meropenem| Merrem| | | |
Cephalosporins (First generation)|
Cefadroxil| Duricef| Good coverage against Gram positive infections.| * Gastrointestinal upset and diarrhea * Nausea (if alcohol taken concurrently) * Allergic reactions| Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.| Cefazolin| Ancef| | | |

Cefalotin or Cefalothin| Keflin| | | |
Cefalexin| Keflex| | | |
Cephalosporins (Second generation)|
Cefaclor| Ceclor| Less gram positive cover, improved gram negative cover.| * Gastrointestinal upset and diarrhea * Nausea (if alcohol taken concurrently) * Allergic reactions| Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.| Cefamandole| Mandol| | | |

Cefoxitin| Mefoxin| | | |
Cefprozil| Cefzil| | | |
Cefuroxime| Ceftin, Zinnat| | | |
Cephalosporins (Third generation)|
Cefixime| Suprax| Improved coverage of Gram negative organisms, exceptPseudomonas. Reduced Gram positive cover.| * Gastrointestinal upset and diarrhea * Nausea (if alcohol taken concurrently) * Allergic reactions| Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.| Cefdinir| Omnicef, Cefdiel| | | |

Cefditoren| Spectracef| | | |
Cefoperazone| Cefobid| | | |
Cefotaxime| Claforan| | | |
Cefpodoxime| Vantin| | | |
Ceftazidime| Fortaz| | | |
Ceftibuten| Cedax| | | |
Ceftizoxime| Cefizox| | | |
Ceftriaxone| Rocephin| | | |
Cephalosporins (Fourth generation)|
Cefepime| Maxipime| Covers pseudomonal infections.| * Gastrointestinal upset and diarrhea * Nausea (if alcohol taken concurrently) * Allergic reactions| Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.| Cephalosporins (Fifth generation)|

Ceftobiprole| Zeftera| Used to treat MRSA| * Gastrointestinal upset and diarrhea * Nausea (if alcohol taken concurrently) * Allergic reactions| Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.| Glycopeptides|

Teicoplanin| Targocid| | |...
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