Answer Key for Practise Exam
c
IB DIPLOMA PROGRAMME
PROGRAMME DU DIPLÔME DU BI
PROGRAMA DEL DIPLOMA DEL BI
SPEC/4/BIOLO/HPM/ENG/TZ0/XX/M
MARKSCHEME
SPECIMEN PAPER
BIOLOGY
Higher Level
Paper 1
2 pages
–2–
SPEC/4/BIOLO/HPM/ENG/TZ0/XX/M
1.
B
16.
C
31.
D
46.
–
2.
C
17.
B
32.
D
47.
–
3.
D
18.
B
33.
A
48.
–
4.
D
19.
B
34.
D
49.
–
5.
D
20.
B
35.
C
50.
–
6.
D
21.
B
36.
D
51.
–
7.
B
22.
B
37.
B
52.
–
8.
B
23.
D
38.
D
53.
–
9.
A
24.
C
39.
A
54.
–
10.
D
25.
D
40.
A
55.
–
11.
C
26.
B
41.
–
56.
–
12.
D
27.
D
42.
–
57.
–
13.
C
28.
C
43.
–
58.
–
14.
D
29.
A
44.
–
59.
–
15.
D
30.
B
45.
–
60.
–
IB DIPLOMA PROGRAMME
PROGRAMME DU DIPLÔME DU BI
PROGRAMA DEL DIPLOMA DEL BI
SPEC/4/BIOLO/HP2/ENG/TZ0/XX/M
MARKSCHEME
SPECIMEN PAPER
BIOLOGY
Higher Level
Paper 2
8 pages
–2–
SPEC/4/BIOLO/HP2/ENG/TZ0/XX/M
Section A
1.
(a)
at lower concentration inhibition is low; as concentration rises from 5 – 20μmol dm 3 there is very little increase in inhibition; from 20μ mol dm 3 inhibition increases in a linear manner; a valid comparison with another of the peptides;
[2 max]
(b)
no effect on S. aureus, inhibits growth of C. albicans; no change on S. aureus as concentration increases, inhibition of C. albicans increases with concentration;
(c)
at lowest (experimental) concentration (LL-37) does not have effect on either; as concentration increases so does inhibition; greater inhibition of C. albicans; effective against C. albicans but not/less effective on S aureus;
(d)
LLG
(e)
18 2 16 /
[3 max]
[1]
16
100% / 8 100%;
2
800% ;
(f)
[2]
LLG/naturally occurring peptide less effective;
LL-37 less effective than GKE/FKR;
LL-37 damages DNA (significantly) at more than 6μmol dm 3 ;
LL-37 may kill cells at higher concentrations;
GKE/FKR could be used at lower concentrations;
GKE/FKR cause slight DNA damage at lower concentrations;
GKE is (slightly) more effective;
GKE causes increased
IB DIPLOMA PROGRAMME
PROGRAMME DU DIPLÔME DU BI
PROGRAMA DEL DIPLOMA DEL BI
SPEC/4/BIOLO/HPM/ENG/TZ0/XX/M
MARKSCHEME
SPECIMEN PAPER
BIOLOGY
Higher Level
Paper 1
2 pages
–2–
SPEC/4/BIOLO/HPM/ENG/TZ0/XX/M
1.
B
16.
C
31.
D
46.
–
2.
C
17.
B
32.
D
47.
–
3.
D
18.
B
33.
A
48.
–
4.
D
19.
B
34.
D
49.
–
5.
D
20.
B
35.
C
50.
–
6.
D
21.
B
36.
D
51.
–
7.
B
22.
B
37.
B
52.
–
8.
B
23.
D
38.
D
53.
–
9.
A
24.
C
39.
A
54.
–
10.
D
25.
D
40.
A
55.
–
11.
C
26.
B
41.
–
56.
–
12.
D
27.
D
42.
–
57.
–
13.
C
28.
C
43.
–
58.
–
14.
D
29.
A
44.
–
59.
–
15.
D
30.
B
45.
–
60.
–
IB DIPLOMA PROGRAMME
PROGRAMME DU DIPLÔME DU BI
PROGRAMA DEL DIPLOMA DEL BI
SPEC/4/BIOLO/HP2/ENG/TZ0/XX/M
MARKSCHEME
SPECIMEN PAPER
BIOLOGY
Higher Level
Paper 2
8 pages
–2–
SPEC/4/BIOLO/HP2/ENG/TZ0/XX/M
Section A
1.
(a)
at lower concentration inhibition is low; as concentration rises from 5 – 20μmol dm 3 there is very little increase in inhibition; from 20μ mol dm 3 inhibition increases in a linear manner; a valid comparison with another of the peptides;
[2 max]
(b)
no effect on S. aureus, inhibits growth of C. albicans; no change on S. aureus as concentration increases, inhibition of C. albicans increases with concentration;
(c)
at lowest (experimental) concentration (LL-37) does not have effect on either; as concentration increases so does inhibition; greater inhibition of C. albicans; effective against C. albicans but not/less effective on S aureus;
(d)
LLG
(e)
18 2 16 /
[3 max]
[1]
16
100% / 8 100%;
2
800% ;
(f)
[2]
LLG/naturally occurring peptide less effective;
LL-37 less effective than GKE/FKR;
LL-37 damages DNA (significantly) at more than 6μmol dm 3 ;
LL-37 may kill cells at higher concentrations;
GKE/FKR could be used at lower concentrations;
GKE/FKR cause slight DNA damage at lower concentrations;
GKE is (slightly) more effective;
GKE causes increased